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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Cyclodextrin based nanosponges: a propitious platform for enhancing the solubility of poorly water-soluble drug. |
| Authors Name: | Sadhana Dhanraj Mane , DR.A.H.Hosmani , Megha Mane , Vinanti Mudgal , Prajkta Waghmare |
| Unique Id: | IJSDR2206085 |
| Published In: | Volume 7 Issue 6, June-2022 |
| Abstract: | The low aqueous solubility of many useful drugs is a current issue in the pharmaceutical industry. Before a new drug can be approved for the market, it must undergo extensive research and testing. The aqueous solubility of a drug is one of the factors that determines its efficacy because it is not easily absorbed by the body. The hydrophobic nature of the drug contributes to its low aqueous solubility. To overcome the challenge of drug insolubility, many methods have been developed. Because cyclodextrins are nontoxic to humans, cyclodextrin-based nanosponges have been used in pharmaceutical and biomedical applications. The use of beta-cyclodextrin as a drug carrier to improve the solubility of poorly soluble drug is the focus of this paper. Under an optical microscope, the product obtained in these conditions has a peculiar morphology; it is made up of spheroidal particles with regular dimensions smaller than 5 microns. The individual particles' spherical shape is a requirement for the polymer to be used in advanced and innovative pharmaceutical applications. |
| Keywords: | Beta-cyclodextrin, Cyclodextrin-based carbonate nanosponge, Cyclodextrin-based carbamate nanosponges, Cyclodextrin-based ester nanosponges |
| Cite Article: | "Cyclodextrin based nanosponges: a propitious platform for enhancing the solubility of poorly water-soluble drug.", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 6, page no.530 - 536, June-2022, Available :http://www.ijsdr.org/papers/IJSDR2206085.pdf |
| Downloads: | 000346989 |
| Publication Details: | Published Paper ID: IJSDR2206085 Registration ID:200796 Published In: Volume 7 Issue 6, June-2022 DOI (Digital Object Identifier): Page No: 530 - 536 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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