Addition of Gourami Fish Scales to Glass Ionomer Cement (GIC) Increases Odontoblast Like Cells Number and Expression of IL-10 (Interleukin-10)

Roedy Budirahardjo , Dyah Setyorini , Sulistiyani , I Dewa Ayu Ratna Dewanti , Eri Hendra Jubhari

Glass Ionomer Cement; gouramy fish scales; Odontoblasts like cells; Interleukin; Immunohistochemistry

Introduction. Fish scales are usually not used anymore or thrown away, in fact they contain organic and inorganic materials that are also found in bone and dentin. Purposed. This research to analyze the addition of gouramy scales powder (GSP) to Glass Ionomer Cement (GIC) on odontoblast count and IL-10 expression in the oral cavity of Wistar rats. Method. we used male Wistar rats C: group mice that did not bore holes in their teeth. Groups in this research, P1: the sample is filled with GIC. P2: GIC + 2.5% GSP. P3: GIC + 5% GSP. P4: GIC + 10% GSP. After 7 days the rats were sacrificed and their teeth were made preparations for odontoblast cells observation (light microscope magnification 400 times) and analysis of IL-10 by immunohistochemical technique. Results. The ANOVA and LSD test confirmed significant differences. The increase in the number of odontoblasts and IL-10 is thought to be due to goramy scales caused by chitin, calcium, amino acids, omega 3, and omega 6. Conclusion. The addition of gouramy scales powder (GSP) to Glass Ionomer Cement (GIC) increased the number of odontoblasts like cells and the expression of IL-10 in the oral cavity of Wistar rats. So that the addition of gouramy fish scales can be considered to improve the quality of GIC.

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"Addition of Gourami Fish Scales to Glass Ionomer Cement (GIC) Increases Odontoblast Like Cells Number and Expression of IL-10 (Interleukin-10)", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.7, Issue 2, page no.63 - 66, February-2022, Available :https://ijsdr.org/papers/IJSDR2202009.pdf

Volume 7 Issue 2, February-2022

Pages : 63 - 66

Paper Reg. ID: IJSDR_193943

Published Paper Id: IJSDR2202009

Downloads: 000347222

Research Area: Biological Science

Country: Jember, East Java, Indonesia

Published Paper PDF: https://ijsdr.org/papers/IJSDR2202009

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2202009

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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