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ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
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Volume 8 | Issue 1

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Paper Title: Preparation and Evaluation of Oral Fast Dissolving Films of Bilastine Using Pullulan
Authors Name: Vaishnavi Ladhake , Samiksha Kadu , Vasihnavi Tayde , Shweta Gawande , Vedanshu Malviya
Unique Id: IJSDR2006046
Published In: Volume 5 Issue 6, June-2020
Abstract: Oral dispersible film of Bilastine was prepared with the solvent casting method using Pullulan as a polymer and glycerine as a plasticizer. The prepared films were then evaluated for the various evaluation parameters such as physical appearance, thickness, folding endurance, in vitro disintegration, mechanical properties, surface pH, drug content uniformity, taste evaluation, in vitro dissolution test. The X6 formulation was found to be optimized and appropriate in its evaluation parameters than compared to other formulation. All the films were transparent and smooth in appearance. The folding endurance was found to be in the range of 83-82, disintegrating was found to be 05-18, thickness was found to be 0.053-0.082mm, tensile strength was found to be 5.09-8.03g/mm2, the % elongation was found to be 14.33-37.68, the maximum % drug release was found to be 98.60% in 30mins. The drug content was found to be 92.14-98.60% with surface pH of 6.4-6.7.
Keywords: Oral Dispersible Film, Pullulan, Glycerine, Bilastine, Solvent Casting.
Cite Article: "Preparation and Evaluation of Oral Fast Dissolving Films of Bilastine Using Pullulan", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.5, Issue 6, page no.282 - 287, June-2020, Available :http://www.ijsdr.org/papers/IJSDR2006046.pdf
Downloads: 000201507
Publication Details: Published Paper ID: IJSDR2006046
Registration ID:191931
Published In: Volume 5 Issue 6, June-2020
DOI (Digital Object Identifier):
Page No: 282 - 287
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

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