A COMPREHENSIVE REVIEW OF FLOATING MICROBALLOONS AS A GASTRORETENTIVE DRUG DELIVERY SYSTEM
Baira varshitha
, G. sneha priya , Dr.G.Uma rani
Microballoons, Gastroretentive drug delivery, Floating drug delivery system, Controlled release, Ethyl cellulose, Solvent evaporation method, Buoyancy, Drug entrapment efficiency, In vitro drug release.
The present work aims to design and evaluate floating microballoons to achieve prolonged gastric retention and controlled drug release. Microballoons were prepared using the emulsion solvent diffusion method, incorporating ethyl cellulose as a release-controlling polymer and calcium silicate as a buoyancy enhancer. The developed formulations were evaluated for their micromeritic properties, particle size, percentage yield, buoyancy behaviour, in vitro drug release, and surface morphology. The optimised formulation demonstrated excellent floating ability for more than 12 hours, with a sustained drug release pattern extending up to 12 hours. Scanning electron microscopy confirmed a spherical shape with a hollow core, which contributes to their low density and buoyant capacity.
"A COMPREHENSIVE REVIEW OF FLOATING MICROBALLOONS AS A GASTRORETENTIVE DRUG DELIVERY SYSTEM
", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.10, Issue 9, page no.a114-a120, September-2025, Available :https://ijsdr.org/papers/IJSDR2509018.pdf
Volume 10
Issue 9,
September-2025
Pages : a114-a120
Paper Reg. ID: IJSDR_304801
Published Paper Id: IJSDR2509018
Downloads: 000109
Research Area: Pharmacy All
Country: Hyderabad, TELANGANA, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
