Investigating reproductive toxicity in male on exposure to monosodium glutamate Using Drosophila melanogaster as an alternative animal model

Antariksha Banik , Dr. Mausumi Ari Acharyya

Monosodium Glutamate / toxicity, Reproductive Toxicity, Drosophila melanogaster / physiology, Sperm Morphology / drug effects, Testis / pathology, Mating Behavior, Animal / drug effects

Monosodium glutamate (MSG), a widely used food additive, has been linked to potential reproductive toxicity, raising concerns about its effects on male fertility. This study investigates the impact of MSG exposure on male reproductive health using Drosophila melanogaster as an alternative model organism. Various reproductive assays, including mating capability, courtship behavior, testicular morphology, and sperm quality assessments, were conducted to evaluate MSG's toxic effects. Results indicate a dose-dependent decline in reproductive performance, characterized by reduced mating success, structural deformities in the testes, and increased abnormalities in sperm morphology. Notably, MSG-treated flies exhibited smaller sperm size, lower sperm viability, and compromised testicular integrity, suggesting significant reproductive toxicity. These findings highlight the potential risks of excessive MSG consumption and underscore the utility of Drosophila melanogaster as a model for studying chemical-induced reproductive toxicity. Further research is warranted to explore underlying molecular mechanisms and establish regulatory guidelines for MSG exposure.

Published Paper   E-Certificate

"Investigating reproductive toxicity in male on exposure to monosodium glutamate Using Drosophila melanogaster as an alternative animal model", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.10, Issue 3, page no.b114-b125, March-2025, Available :https://ijsdr.org/papers/IJSDR2503116.pdf

Volume 10 Issue 3, March-2025

Pages : b114-b125

Paper Reg. ID: IJSDR_300978

Published Paper Id: IJSDR2503116

Downloads: 000168

Research Area: Life Sciences All

Country: Kolkata, West Bengal, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2503116

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2503116

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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