Red Cell Distribution Width in Predicting Severity of COPD: A Cross-Sectional Study at a Tertiary Care Centre.
Dr. Mohammed Sameer Kundale
, Dr. Pragati Rao D , Dr. Sruthy Vijayan , Dr. Nirantha S P , Dr. Shashidhar S Vananjakar
COPD, Spirometry, GOLD, RDW, CAT score
Background: COPD is a chronic inflammatory disease with persistent airflow limitation. GOLD guidelines use post-bronchodilator FEV1 for severity assessment, but spirometry can be challenging during exacerbations. Red Cell Distribution Width (RDW) may serve as a simple biomarker for COPD severity.
Objectives:
1. Assess RDW’s role in predicting COPD severity.
2. Correlate RDW with COPD Assessment Test (CAT) scores.
Methodology: This cross-sectional study (August 2022–July 2024) at Ramaiah Hospitals included COPD patients meeting specific criteria. Spirometry, complete blood counts, and CAT scores were analyzed. GOLD staging classified severity. Statistical analysis used ANOVA and Pearson correlation (p < 0.05 significant).
Results: Among 80 COPD patients (91.3% male, 75% aged 61–80), common symptoms included cough (77.5%) and breathlessness (73.8%). Smoking (73.8%), occupational (10%), and biomass (11.3%) exposures were noted. RDW values increased with GOLD stage progression and correlated positively with CAT scores (r = 0.250, p = 0.027) and negatively with FEV1 (r = -0.517, p < 0.001).
Conclusion: RDW correlates with COPD severity, positively with CAT scores and negatively with FEV1, highlighting its potential as a non-invasive ,novel biomarker for disease assessment and management.
"Red Cell Distribution Width in Predicting Severity of COPD: A Cross-Sectional Study at a Tertiary Care Centre.", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.10, Issue 3, page no.a308-a315, March-2025, Available :https://ijsdr.org/papers/IJSDR2503035.pdf
Volume 10
Issue 3,
March-2025
Pages : a308-a315
Paper Reg. ID: IJSDR_300820
Published Paper Id: IJSDR2503035
Downloads: 000197
Research Area: Humanities All
Country: Bangalore, KARNATAKA, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
