Fast Dissolving Drug Delivery Systems (FDDS): A Review

Rohit , Rajkumar Mishra , Dr. Amrita Singh , Snehil Singh , Dr. Bhanu P. S. Sagar

Fast dissolving drug delivery system, Super-disintegrants, disintegration, dissolution, dispersible, mouth dissolving tablets,

The ultimate objective of fast dissolving drug delivery system is to provide the tablet that quickly dissolves upon contact with saliva and also provide the good mouth feel. Recently more stress is laid down on the development of organoleptically elegant and patient friendly drug delivery systems for paedriatic and geriatric patients. Patient convenience and compliance oriented research has resulted in bringing out many safer and newer drug delivery systems. Rapidly disintegrating / dissolving tablet is one such example, for the reason of rapid disintegration or dissolution in mouth with little amount of water or even with saliva. Significance of this drug delivery system includes administration without water, accuracy of dosage forms, ease of portability and alternative to liquid dosage forms, ideal for paedriatic and geriatric patients and rapid onset of action. Fast-dissolving tablets are a cutting-edge method of drug delivery that, with or without water consumption, dissolve, disintegrate, or distribute the API in saliva in a matter of seconds. The absorption and start of the therapeutic action occur more quickly the faster the drug dissolves in the solution. Both natural and artificial super-disintegrants, such as mucilage, poly vinyl pyrollidone, sodium starch glycolate (primogel), cross-linked carboxymethyl cellulose (croscarmellose), and others, offer instant tablet disintegration and make it easier to create delivery systems with desired properties. For medications used in emergencies, such as cardiac agents, asthama, brain stroke, anti-hyperlipidemic, etc., these kinds of formulations are frequently advisedThe ultimate objective of fast dissolving drug delivery system is to provide the tablet that quickly dissolves upon contact with saliva and also provide the good mouth feel. Recently more stress is laid down on the development of organoleptically elegant and patient friendly drug delivery systems for paedriatic and geriatric patients. Patient convenience and compliance oriented research has resulted in bringing out many safer and newer drug delivery systems. Rapidly disintegrating / dissolving tablet is one such example, for the reason of rapid disintegration or dissolution in mouth with little amount of water or even with saliva. Significance of this drug delivery system includes administration without water, accuracy of dosage forms, ease of portability and alternative to liquid dosage forms, ideal for paedriatic and geriatric patients and rapid onset of action. Fast-dissolving tablets are a cutting-edge method of drug delivery that, with or without water consumption, dissolve, disintegrate, or distribute the API in saliva in a matter of seconds. The absorption and start of the therapeutic action occur more quickly the faster the drug dissolves in the solution. Both natural and artificial super-disintegrants, such as mucilage, poly vinyl pyrollidone, sodium starch glycolate (primogel), cross-linked carboxymethyl cellulose (croscarmellose), and others, offer instant tablet disintegration and make it easier to create delivery systems with desired properties. For medications used in emergencies, such as cardiac agents, asthama, brain stroke, anti-hyperlipidemic, etc., these kinds of formulations are frequently advised

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"Fast Dissolving Drug Delivery Systems (FDDS): A Review", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 10, page no.421 - 436, October-2024, Available :https://ijsdr.org/papers/IJSDR2410050.pdf

Volume 9 Issue 10, October-2024

Pages : 421 - 436

Paper Reg. ID: IJSDR_212632

Published Paper Id: IJSDR2410050

Downloads: 000347326

Research Area: Chemistry

Country: -, -, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2410050

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2410050

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

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