Comparative Efficacy of Propofol and Dexmedetomidine in Controlled Hypotension for Enhanced Visualization During Functional Endoscopic Sinus Surgery
DR. SHISHIRA SUHANI RAJ TALLAPELLI
, DR. DIVYA PADETI , DR. NEELIMA TALLAPUDI , DR. PASUMARTHI DEVI VENKATA SATYA SRI
Dexmedetomidine, Propofol, Hypotensive anaesthesia, mean arterial pressure, blood loss
Abstract Background: Functional Endoscopic Sinus Surgery (FESS) is prone to intraoperative bleeding, which can compromise surgical visibility and increase complications. This study aimed to compare the efficacy of propofol and dexmedetomidine in achieving controlled hypotension during FESS. Methods: In this randomized prospective study, 40 patients aged 20 to 50 years with ASA physical status I and II were assigned to receive either dexmedetomidine (Group D) or propofol (Group P) during elective FESS. Key outcomes measured included heart rate, mean arterial pressure (MAP), intraoperative blood loss, and quality of the surgical field, evaluated using the Fromme-Boezzart Scale. Results: The demographic characteristics of both groups were comparable. Mean heart rate was significantly lower in Group D from 30 minutes onward (p < 0.05). MAP was also significantly lower in Group D, with statistical significance noted from the 20th minute (p < 0.05). Mean blood loss was 85 ± 15 mL for dexmedetomidine and 90 ± 12 mL for propofol, demonstrating statistical significance (p < 0.05). However, the quality of the surgical field did not show significant differences between the groups (p = 0.460). Conclusion: Dexmedetomidine demonstrated a favorable hemodynamic profile with lower heart rates and MAP, alongside reduced blood loss compared to propofol during FESS. These findings suggest that dexmedetomidine may be beneficial in controlled hypotension for enhancing surgical conditions. Further research with larger sample sizes is needed to corroborate these results and assess long-term outcomes.
"Comparative Efficacy of Propofol and Dexmedetomidine in Controlled Hypotension for Enhanced Visualization During Functional Endoscopic Sinus Surgery", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 10, page no.346 - 351, October-2024, Available :https://ijsdr.org/papers/IJSDR2410043.pdf
Volume 9
Issue 10,
October-2024
Pages : 346 - 351
Paper Reg. ID: IJSDR_212613
Published Paper Id: IJSDR2410043
Downloads: 000347062
Research Area: Medical Science
Country: NELLIMARLA, Andhra Pradesh, India
DOI: https://doi.org/10.5281/zenodo.13998019
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
