INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Comparative Efficacy of Propofol and Dexmedetomidine in Controlled Hypotension for Enhanced Visualization During Functional Endoscopic Sinus Surgery
Authors Name:
DR. SHISHIRA SUHANI RAJ TALLAPELLI
, DR. DIVYA PADETI , DR. NEELIMA TALLAPUDI , DR. PASUMARTHI DEVI VENKATA SATYA SRI
Unique Id:
IJSDR2410043
Published In:
Volume 9 Issue 10, October-2024
Abstract:
Abstract Background: Functional Endoscopic Sinus Surgery (FESS) is prone to intraoperative bleeding, which can compromise surgical visibility and increase complications. This study aimed to compare the efficacy of propofol and dexmedetomidine in achieving controlled hypotension during FESS. Methods: In this randomized prospective study, 40 patients aged 20 to 50 years with ASA physical status I and II were assigned to receive either dexmedetomidine (Group D) or propofol (Group P) during elective FESS. Key outcomes measured included heart rate, mean arterial pressure (MAP), intraoperative blood loss, and quality of the surgical field, evaluated using the Fromme-Boezzart Scale. Results: The demographic characteristics of both groups were comparable. Mean heart rate was significantly lower in Group D from 30 minutes onward (p < 0.05). MAP was also significantly lower in Group D, with statistical significance noted from the 20th minute (p < 0.05). Mean blood loss was 85 ± 15 mL for dexmedetomidine and 90 ± 12 mL for propofol, demonstrating statistical significance (p < 0.05). However, the quality of the surgical field did not show significant differences between the groups (p = 0.460). Conclusion: Dexmedetomidine demonstrated a favorable hemodynamic profile with lower heart rates and MAP, alongside reduced blood loss compared to propofol during FESS. These findings suggest that dexmedetomidine may be beneficial in controlled hypotension for enhancing surgical conditions. Further research with larger sample sizes is needed to corroborate these results and assess long-term outcomes.
Keywords:
Dexmedetomidine, Propofol, Hypotensive anaesthesia, mean arterial pressure, blood loss
Cite Article:
"Comparative Efficacy of Propofol and Dexmedetomidine in Controlled Hypotension for Enhanced Visualization During Functional Endoscopic Sinus Surgery", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 10, page no.346 - 351, October-2024, Available :http://www.ijsdr.org/papers/IJSDR2410043.pdf
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Publication Details:
Published Paper ID: IJSDR2410043
Registration ID:212613
Published In: Volume 9 Issue 10, October-2024
DOI (Digital Object Identifier): https://doi.org/10.5281/zenodo.13998019
Page No: 346 - 351
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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