EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF GLYCYRRHIZA GLABRA LINN ON PARACETAMOL INDUCED LIVER DAMAGE IN RATS
Hepatoprotective Activity, Glycyrrhiza Glabra Linn, Paracetamol Induced Liver
the results of this study demonstrate that the methanol extract of Glycyrrhiza glabra Linn. leaves have a potent hepatoprotective action against paracetamol induced hepatic damage in rats. It’s mode in affording the hepatoprotective activity against paracetamol induced liver damage may be due to cell membrane stabilization, hepatic cell regeneration and enhancement of antioxidant enzymes such as catalase, superoxide dismutase and glutathione peroxidase production. In spite of the unknown mechanism of action, the obvious hepatoprotective effect of Glycyrrhiza glabra Linn. leaves on paracetamol induced liver damage may have potential in clinical applications. The hepatoprotective and antioxidant potential of extract could have been brought about by various phytochemical principles i.e flavonoids, alkaloids, phenolics and tannins present in Glycyrrhiza glabra Linn. leaves.
"EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF GLYCYRRHIZA GLABRA LINN ON PARACETAMOL INDUCED LIVER DAMAGE IN RATS", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 10, page no.94 - 106, October-2024, Available :https://ijsdr.org/papers/IJSDR2410011.pdf
Volume 9
Issue 10,
October-2024
Pages : 94 - 106
Paper Reg. ID: IJSDR_212528
Published Paper Id: IJSDR2410011
Downloads: 000347070
Research Area: Pharmacy
Country: Hyderabad, Telangana, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave