INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF GLYCYRRHIZA GLABRA LINN ON PARACETAMOL INDUCED LIVER DAMAGE IN RATS
Authors Name:
Darugupally yashaswini
Unique Id:
IJSDR2410011
Published In:
Volume 9 Issue 10, October-2024
Abstract:
the results of this study demonstrate that the methanol extract of Glycyrrhiza glabra Linn. leaves have a potent hepatoprotective action against paracetamol induced hepatic damage in rats. It’s mode in affording the hepatoprotective activity against paracetamol induced liver damage may be due to cell membrane stabilization, hepatic cell regeneration and enhancement of antioxidant enzymes such as catalase, superoxide dismutase and glutathione peroxidase production. In spite of the unknown mechanism of action, the obvious hepatoprotective effect of Glycyrrhiza glabra Linn. leaves on paracetamol induced liver damage may have potential in clinical applications. The hepatoprotective and antioxidant potential of extract could have been brought about by various phytochemical principles i.e flavonoids, alkaloids, phenolics and tannins present in Glycyrrhiza glabra Linn. leaves.
Keywords:
Hepatoprotective Activity, Glycyrrhiza Glabra Linn, Paracetamol Induced Liver
Cite Article:
"EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF GLYCYRRHIZA GLABRA LINN ON PARACETAMOL INDUCED LIVER DAMAGE IN RATS", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 10, page no.94 - 106, October-2024, Available :http://www.ijsdr.org/papers/IJSDR2410011.pdf
Downloads:
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Publication Details:
Published Paper ID: IJSDR2410011
Registration ID:212528
Published In: Volume 9 Issue 10, October-2024
DOI (Digital Object Identifier):
Page No: 94 - 106
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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