PHYTOCHEMICAL SCREENING AND EVALUATION OF ANTIDEPRESSANT ACTIVITY OF ETHANOLIC EXTRACT OF LEAVES OF AMMANIA BACCIFERA

Mohammed Amer

Phytochemical Screening, Antidepressant Activity, Ethanolic Extract, Leaves, Ammania Baccifera

The results of phytochemical analysis showed the presence of phytoconstitutents other than Flavonoids like Alkaloids,Triterpenes, Tannins, saponins, glycosides etc .,in EEAB. Previous research reports reveal that the presence of saponins and flavonoids [19] attributed to the anti-depressant activity of several plants. Depression is characterized by emotional symptoms such as hopelessness, apathy, and loss of self -confidence as well as biological symptoms like psychomotor retardation, loss of libido, sleep disturbances and loss of appetite. The study was conducted to assess the anti- depressant activity of EEAB using FST and TST. Exposure to stress place an important role in depression. FST and TST models of depression which provides a rapid and reliable behavior screening test for anti- depressants. In this study, treatment of EEAB decreased the duration of immobility in FST and in TST which reveals the antidepressant activity of EEAB. The presence of Phytoconstituents like saponins and flavonoids could attribute to the antidepressant activity of EEAB. However further studies like receptor binding assay interaction studies and neurotransmitter assay are required for elucidating the mechanism of action.

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"PHYTOCHEMICAL SCREENING AND EVALUATION OF ANTIDEPRESSANT ACTIVITY OF ETHANOLIC EXTRACT OF LEAVES OF AMMANIA BACCIFERA", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 10, page no.54 - 61, October-2024, Available :https://ijsdr.org/papers/IJSDR2410008.pdf

Volume 9 Issue 10, October-2024

Pages : 54 - 61

Paper Reg. ID: IJSDR_212522

Published Paper Id: IJSDR2410008

Downloads: 000347233

Research Area: Pharmacy

Country: Hyderabad, Telangana, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2410008

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2410008

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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