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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | A Review On Solid Lipid Nanoparticles Based Topical Gel |
| Authors Name: | Smital Patil , Vrushali Jadhav |
| Unique Id: | IJSDR2407003 |
| Published In: | Volume 9 Issue 7, July-2024 |
| Abstract: | Abstract : This review on solid lipid nanoparticles for topical gel formulation explores the potential of using the solid lipid nanoparticles (SLNs) for formulating them in a topical gel. Researchers have prepared SLNs by incorporating piroxicam into polymer matrix using various methods of preparation but mainly focusing on a highly recommended and used method, that is; by solvent extraction method and high-pressure homogenization. They have also highlighted the advantages of using SLNs as a delivery system in topical gel formulation. Now-a-days topical gels are extensively used in the treatment of various diseases and skin conditions and the new emerging novel drug delivery system- SLNs, just blend with each other well with respect to their properties and the ability to increase the therapeutic efficacy of the drugs having poor solubility and bioavailability and including drugs that shows systemic side effects. The formulation studies of SLNs based topical gels also showed satisfactory results like that of the reported standards for all characterization such as the organoleptic properties, particle size, polydispersity index, zeta potential, calibration curve, differential scanning calorimeters and partition coefficient. Overall, this review is about the SLNs which are formulated in a topical gel can be used for a variety of applications. This review also provides an overview on the method of preparations used by the researchers and some other key points which are highlighted by the authors in their topic. |
| Keywords: | Keywords : Solid lipid nanoparticles, topical drug delivery, solvent extraction, high pressure homogenization. |
| Cite Article: | "A Review On Solid Lipid Nanoparticles Based Topical Gel", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.9, Issue 7, page no.18 - 26, July-2024, Available :http://www.ijsdr.org/papers/IJSDR2407003.pdf |
| Downloads: | 000346989 |
| Publication Details: | Published Paper ID: IJSDR2407003 Registration ID:211907 Published In: Volume 9 Issue 7, July-2024 DOI (Digital Object Identifier): Page No: 18 - 26 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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