EFFICACY OF COMBINED USAGE OF FOLEYS WITH MISOPROSTOL FOR SECOND AND EARLY THIRD TRIMESTER TERMINATION IN PREGNANCY
Intracervical Foleys catheter, Misoprostol, Second trimester termination, Early third trimester termination, Induction to delivery interval (ID interval), D and E.
Background : Second trimester pregnancy losses constitute 10 to 15% of all pregnancy losses. Mid trimester pregnancy termination is a difficult procedure. Maternal mortality rate is 0.4/1 lakh, but in mid
trimester 10.4/1 lakh, various methods including medical and mechanical have been used for induction.
Misoprostol is safe, effective easily applicable non-invasive for mid trimester.
In this trial the combination of intracervical foleys catheter and misoprostol was taken to reduce the dose of misoprostol and reduce the induction delivery interval.
Objective: To know the effectiveness and safety of combined intracervical foleys catheter and misoprostol use for mid trimester and early third trimester termination.
Method: We conducted a retrospective study from July 2022 - June 2023 of selective patients with gestational age between 14 weeks to 34 weeks. 14 F foleys catheter was inserted intra-cervically and instilled 30 cc sterile water. Simultaneously, misoprostol was given vaginally. Patients received misoprostol 200 μg in the second
trimester and 100mcg in the early third trimester at the time of intracervical foley's placement and then 4th hourly till intracervical foley's expulsion. We primarily evaluated effectiveness and secondarily safety, complications and total dosage of misoprostol used.
Result : Out of 30 cases analysed, mean age of the group was 24years, for one patient more than three doses of
misoprostol was required. Mean time of intracervical foley’s expulsion to foetus expulsion is 1 hour, induction delivery interval on an average 12 hours, (minimum interval-4 hours, maximum interval -18 hours), hysterotomy was done in 1 patient, 2 patients required ICU admissions for medical conditions , 1 patient required blood transfusion, dilatation and evacuation was performed for 2 cases.
Conclusion: Combination of intracervical foleys and vaginal misoprostol is a safe and effective method of termination of pregnancy in mid-trimester and early third trimester.
"EFFICACY OF COMBINED USAGE OF FOLEYS WITH MISOPROSTOL FOR SECOND AND EARLY THIRD TRIMESTER TERMINATION IN PREGNANCY", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 5, page no.1321 - 1325, May-2024, Available :https://ijsdr.org/papers/IJSDR2405176.pdf
Volume 9
Issue 5,
May-2024
Pages : 1321 - 1325
Paper Reg. ID: IJSDR_211503
Published Paper Id: IJSDR2405176
Downloads: 000347387
Research Area: Medical Science
Country: Shorapur , Karnataka, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
