HRCT Perspectives on Centri-lobular Pulmonary Nodules: Diagnostic Pathways

Dr. B. Sridhar , Dr. B. Kranthi Abhishek , Dr. Jajjala Kranthi Kumar , Dr. Udara Rajesh , Dr. G. S. Kejiriwal

Centri-lobular nodules, High-resolution computed tomography (HRCT), Maximum intensity projection (MIP), Diffuse pulmonary nodules, Infection/inflammation, Acute viral bronchiolitis, Inhalation bronchiolitis, Diagnostic algorithm

Abstract Background: Centri-lobular nodules represent the predominant pattern of diffuse pulmonary nodules identified on high-resolution computed tomography (HRCT). Leveraging HRCT with advanced post-processing techniques, such as maximum intensity projection (MIP), enhances the visibility of centri-lobular nodules. This study aims to underscore the pivotal role of HRCT and its reconstruction capabilities in detecting and characterizing centri-lobular pulmonary nodules. Additionally, it seeks to elucidate the most frequent associated findings and establish correlations with clinical presentations to facilitate accurate diagnosis. Results: The study encompassed 58 patients, comprising 41.4% males and 58.6% females, with ages ranging from 2 to 67 years (mean age: 25.69 years). Analysis revealed patterns in centri-lobular nodule numbers, distribution, shape, and concomitant HRCT chest findings. The top three etiological diagnoses included infection/inflammation in 50.0% of cases, acute viral bronchiolitis in 27.6%, and inhalation bronchiolitis in 19.0% of cases. Correlation between HRCT findings and clinical diagnosis facilitated the development of a diagnostic algorithm for various etiologies of centri-lobular pulmonary nodules. Conclusions: HRCT emerges as a valuable modality for both detecting and characterizing centri-lobular pulmonary nodules. Its utility extends to distinguishing between diverse etiologies presenting with centri-lobular nodularity. Moreover, the integration of associated features and a multidisciplinary approach proves indispensable for refining the diagnosis of the predominant etiology.

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"HRCT Perspectives on Centri-lobular Pulmonary Nodules: Diagnostic Pathways", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 5, page no.1008 - 1026, May-2024, Available :https://ijsdr.org/papers/IJSDR2405135.pdf

Volume 9 Issue 5, May-2024

Pages : 1008 - 1026

Paper Reg. ID: IJSDR_211444

Published Paper Id: IJSDR2405135

Downloads: 000347374

Research Area: Medical Science

Country: Vizianagaram, Andhra Pradesh, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2405135

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2405135

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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