The Role of Susceptibility Weighted Imaging in Evaluating Intra-Arterial Thrombus for Acute Ischemic Stroke
Dr. Udara Rajesh
, Dr Ankathi Hemanth Varma , Dr R Mrudula , Dr G Rohan , Dr G S Kejiriwal
MRI, Susceptibility Weighted Imaging, Magnetic Resonance Angiography, Acute Ischemic Stroke, Thrombus Detection
Abstract Background: Ischemic stroke is a significant cause of death and long-term disability. Thrombolytic therapy is effective for ischemic strokes treated within 4.5 hours of symptom onset. While arterial occlusions are commonly identified using digital subtraction angiography (DSA), magnetic resonance angiography (MRA), and computed tomography angiography (CTA), these methods do not provide detailed information on thrombus composition and formation time. Susceptibility weighted imaging (SWI) is gaining attention for its ability to detect thrombi in acute ischemic stroke, revealing them as hypointense susceptibility vessel signs (SVS) in the affected regions. Results: In our study, 97 patients were found to have thrombi using MRA, with the M1 segment of the middle cerebral artery (MCA) being the most frequently affected (57.6%). SWI detected intra-arterial thrombi in 122 patients, significantly more than the 97 detected by MRA (P = 0.0002). All patients with thrombi identified by SWI exhibited a positive susceptibility sign. Among these patients, 88.8% had a solitary thrombus, and 11.2% had multiple thrombi. MRA did not identify any distant thrombi. Additionally, 81% of patients with an abnormally prominent vessel sign (APVS) on SWI showed parenchymal changes in these regions. The caudate nucleus, internal capsule, and lentiform nucleus were the least affected areas. All patients with an APVS had arterial occlusion, compared to only 9 patients without an APVS (P = 0.0001). Conclusion: SWI is highly effective in detecting peripheral thrombi in acute ischemic stroke patients. SWI and MRA together improve the visualization of occluded vessels. We recommend incorporating SWI into routine MRI protocols for acute stroke assessment.
"The Role of Susceptibility Weighted Imaging in Evaluating Intra-Arterial Thrombus for Acute Ischemic Stroke", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 5, page no.943 - 951, May-2024, Available :https://ijsdr.org/papers/IJSDR2405126.pdf
Volume 9
Issue 5,
May-2024
Pages : 943 - 951
Paper Reg. ID: IJSDR_211455
Published Paper Id: IJSDR2405126
Downloads: 000347303
Research Area: Medical Science
Country: VIZIANAGARAM, ANDHRA PRADESH, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
