Impact of Anatomical Variations in the Posterior Circle of Willis on Brain Infarction Patterns
Dr. Avala Varun Sai
, Dr. Pawar Swathi , Dr. B. Nuthan , Dr.G.S Kejriwal
Circle of Willis, MR angiogram, Posterior cerebral artery, Posterior communicating artery, Brain infarction.
Abstract Background: The link between anatomical variations in the circle of Willis and brain infarction is debated. This study examines how variations in the posterior part of the circle of Willis, as seen on MR angiography (MRA), relate to ischemic infarctions in different brain regions. Methods: This cross-sectional study included consecutive patients undergoing brain MRI and MRA for suspected strokes. We analyzed the prevalence of anatomical variations, including the persistent fetal origin of the posterior cerebral artery (fPCA) and hypoplastic/aplastic posterior communicating artery (PCoA), and their association with infarctions in various brain regions. Results: We enrolled 298 patients (155 men, 143 women; mean age 57±15) and divided them into two groups: those with infarctions (n=142) and those without (n=156). Persistent fetal origin of the posterior cerebral artery was found in 63 patients (21.1%), and 231 patients (77.5%) had hypoplastic/aplastic PCoA. There was no significant overall correlation between fPCA or PCoA hypoplasia/aplasia and the presence of infarction. However, thalamic infarctions were more frequent in patients with hypoplastic/aplastic PCoA (17/101, 16.8%) compared to those without this variation (1/41, 2.4%) (p=0.024). No significant difference in infarction frequency across brain territories was observed between patients with and without ipsilateral fPCA variations. Conclusions: In patients with brain infarctions, an aplastic or hypoplastic ipsilateral PCoA is linked to a higher incidence of thalamic infarctions. Keywords: Circle of Willis, MR angiogram, Posterior cerebral artery, Posterior communicating artery, Brain infarction.
"Impact of Anatomical Variations in the Posterior Circle of Willis on Brain Infarction Patterns", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 5, page no.813 - 819, May-2024, Available :https://ijsdr.org/papers/IJSDR2405111.pdf
Volume 9
Issue 5,
May-2024
Pages : 813 - 819
Paper Reg. ID: IJSDR_211410
Published Paper Id: IJSDR2405111
Downloads: 000347401
Research Area: Medical Science
Country: Vizianagaram, Andhra pradesh, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
