Quantitative assessment of leukocyte counts in different grades of functional lung impairment in obstructive airway disease patients

Dr.Kanmi Ningshen , Dr.Ashem Nandarani Devi , Dr.Mayanglambam Sangeeta Devi , Dr. Soreingam Ragui A , Dr.Rajkumari Kshemitra

: Asthma, COPD, OAD, FEV1% predicted, leukocyte counts

: Systemic inflammation is associated with impaired lung function and inflammation is a part of Obstructive Airway Disease (OAD). COPD and bronchial asthma are the two most common OAD. This study was done to grade the severity of functional lung impairment and measure the circulating levels of leukocytes in different grades of severity. and to determine the possible relation between the severity of functional lung impairment and the leukocytes levels. A cross-sectional study enrolling 40 COPD & 25 asthmatic patients of both sexes. Lung function was studied, then absolute neutrophil count, absolute eosinophil count, absolute basophil count, absolute lymphocyte count and absolute monocyte count were determined using suitable diluting fluids. Out of 40 COPD patients, 12.5 % of patients had mild, 20% had moderate, 40% had severe and 27.5% had very severe COPD. Out of 25 asthma patients, 48% had mild, 32% had moderate and 20% had severe asthma. Significant increase in neutrophil count with the increase in COPD severity and with the increase in asthma severity, eosinophil count increases significantly. Significant inverse correlation between neutrophil count and FEV1 in COPD patients, and eosinophil count and FEV1 in asthma patients was seen. Index Terms : Asthma, COPD, OAD, FEV1% predicted, leukocyte counts

Published Paper   E-Certificate

"Quantitative assessment of leukocyte counts in different grades of functional lung impairment in obstructive airway disease patients", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 5, page no.308 - 312, May-2024, Available :https://ijsdr.org/papers/IJSDR2405042.pdf

Volume 9 Issue 5, May-2024

Pages : 308 - 312

Paper Reg. ID: IJSDR_211287

Published Paper Id: IJSDR2405042

Downloads: 000347349

Research Area: Medical Science

Country: IMPHAL EAST, MANIPUR, INDIA

Published Paper PDF: https://ijsdr.org/papers/IJSDR2405042

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2405042

DOI: https://doi.org/10.5281/zenodo.11213824

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition