Preparation of hollow microspere loaded with Anti-Infective drug (Cefexime)
Dighe Jaideep Appasaheb
, Dighe Vishal Bhausaheb , Nirmal Tejal
Cefixime, Hollow Microspheres, Sustained Drug Delivery, Invitro drug release, Pharmacokinetics.
In the present study an attempt was made to prepare Hollow Microspheres loaded with an Anti-Infective Drug. Cefixime is a third- generation cephalosporin antibiotic which is highly effective against various infections. Different formulations were prepared by Emulsion Solvent Diffusion method. FTIR and DSC studies confirme¬¬d that there was no interaction between drug and the polymers. Particle size for all formulations were within the range of 560-570 nm respectively. The images from SEM revealed that the particles were spherical in shape. The drug entrapment efficiency of formulations was found to be in the range of 89.34%. Thus, the prepared Hollow Microspheres proved to maintain the therapeutic index over a continued period of time and be a potential candidate as a sustained drug delivery system.
"Preparation of hollow microspere loaded with Anti-Infective drug (Cefexime)", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 5, page no.184 - 190, May-2024, Available :https://ijsdr.org/papers/IJSDR2405024.pdf
Volume 9
Issue 5,
May-2024
Pages : 184 - 190
Paper Reg. ID: IJSDR_211201
Published Paper Id: IJSDR2405024
Downloads: 000347450
Research Area: Pharmacy
Country: Ahmednagar, Maharashtra, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
