Exploring herbal and current medicines: A comprehensive review on integrative approaches for ulcerative colitis

Arvind T , S.Madhu , P.Amudha

Chinese medicines, herbal medicines, ulcerative colitis, management of ulcerative colitis

Ulcerative colitis (UC) is a chronic and recurring gastrointestinal disease with a rising global incidence, impacting individuals' quality of life. This comprehensive review explores the causes, prevalence, pathophysiology, and various treatment options for UC, emphasizing the need for personalized therapeutic approaches. The intricate signaling pathways, including NF-κB, JAK-STAT, MAPK, Wnt/β-Catenin, TLR-MyD88, and PI3K-Akt-mTOR, play crucial roles in UC pathogenesis, providing targets for novel therapies. The diagnosis involves clinical history, stool tests, colonoscopy, and imaging, while treatment includes medications, surgery, and emerging therapies. Herbal and Chinese medicines are gaining attention, with current research highlighting their bioactivity and clinical efficacy. However, challenges such as lack of standardization and safety concerns must be considered. Managing UC involves a holistic approach, integrating medication, dietary changes, and surgical interventions, recognizing the impact on patients' quality of life. Ongoing research aims to unravel UC complexities, paving the way for personalized and targeted therapies to address the evolving landscape of this challenging condition. The article underscores the importance of addressing economic burdens, optimizing resource allocation, and fostering continuous research to improve treatment options and patient outcomes.

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"Exploring herbal and current medicines: A comprehensive review on integrative approaches for ulcerative colitis ", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 3, page no.382 - 392, March-2024, Available :https://ijsdr.org/papers/IJSDR2403057.pdf

Volume 9 Issue 3, March-2024

Pages : 382 - 392

Paper Reg. ID: IJSDR_210383

Published Paper Id: IJSDR2403057

Downloads: 000347086

Research Area: Pharmacy

Country: Chennai, Tamil Nadu, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2403057

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2403057

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition