Role of MRI in Evaluation of Ring Enhancing Lesions of Brain in Correlation with MR Spectroscopy

Dr Chiranth Gowda H P , Dr Gautam Mutu , Dr Anuraj

Keywords: Choline, Magnetic Resonance Imaging, Metabolites, MRI, MRS, Ring Enhancing Lesions, Tuberculoma.

Abstract: Introduction: Ring enhancing lesions of the brain though common on neuroimaging are always challenging for radiologists to diagnose because of their varied etiologies. MRI plays a significant role in the early detection and advanced techniques like MR Spectroscopy increase the chances of successful diagnosis by differentiating infectious lesions from non-infectious lesions. Objectives: 1. To establish a differential diagnosis of the various ring enhancing lesions on conventional MRI. 2. To study the characteristic imaging findings of various ring enhancing lesions on MRI. 3. To study the role of MR spectroscopy in the evaluation of various ring enhancing lesions in the brain with a single voxel proton MR spectroscopy. Material and Methods: A prospective observational study was conducted in the Radiology department of a tertiary hospital for a duration of 2 years which included 44 patients. MRI along with MRS was performed on these patients. Results: Among 44 patients, various ring enhancing lesions (REL’s) detected on MRI were tuberculomas (20, 45%) which were the most common followed by, NCC (8, 18%), abscesses (6, 14%), metastases (5, 11%), primary brain tumors (3, 7%) and toxoplasmosis (2, 5%). On MR spectroscopy, Choline peak was observed in 20 (45%) cases, Lipid peak was present in 31 (70%) cases, Lactate peak in 27 (61%) cases reduced NAA peak in 7 (16%) cases and amino acids in 6 (14%) cases. Choline/creatine ratio of <1 was seen in 10 (23%) of the NCC cases, Choline/creatine ratio of >1-2 was seen in 20 (45%) of the NCC cases, Choline/creatine ratio of >2 was seen in 9 (20%) of the NCC cases Conclusion: In this study, MRI and MRS played a pivotal role in successful diagnosis of various ring enhancing lesions which helped in the initiating the treatment among these patients accordingly.

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"Role of MRI in Evaluation of Ring Enhancing Lesions of Brain in Correlation with MR Spectroscopy", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 1, page no.517 - 526, January-2024, Available :https://ijsdr.org/papers/IJSDR2401075.pdf

Volume 9 Issue 1, January-2024

Pages : 517 - 526

Paper Reg. ID: IJSDR_209917

Published Paper Id: IJSDR2401075

Downloads: 000347346

Research Area: Health Science 

Country: Kambipura, Karnataka, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2401075

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2401075

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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