Method to boost solubility
Vaishnavi Bhaskar Borgaonkar
, Achal Harinarayan Yelane
solubility, permeability, bioavailability, biopharmaceutical classification system, absorption.
The process of a solid dissolving in a liquid phase to create a homogenous mixture is known as solubility. A crucial factor in getting the right quantity of drug into the bloodstream to show a pharmacological effect is solubility. Low water solubility of the novel therapeutic compound is the main issue with formulation. Poorly aqueous soluble medications need substantial dosages to reach their maximum therapeutic plasma concentration after oral delivery. Using the biopharmaceutical classification system (BCS), substances are categorized according to their solubility and permeability. Regulatory agencies and health organizations have adopted this categorization system to enable dissolution to be used to verify bioequivalence for highly soluble and highly permeable chemicals. Drugs with poor water solubility dissolve slowly, which reduces their bioavailability when taken orally. This review article aims to increase bioavailability and promote efficient absorption.
"Method to boost solubility", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 1, page no.404 - 409, January-2024, Available :https://ijsdr.org/papers/IJSDR2401059.pdf
Volume 9
Issue 1,
January-2024
Pages : 404 - 409
Paper Reg. ID: IJSDR_209869
Published Paper Id: IJSDR2401059
Downloads: 000347204
Research Area: Pharmacy
Country: Beed, maharashtra, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave