A Review on the tumour immune microenvironment and the emergence of mRNA vaccines as a novel therapeutic strategy
Advay Gupta
, Matthew Hill
Cancer, Immunology, mRNA vaccines
Cancer is the second leading cause of death in the world. The immune system has been shown to be a critical regulator of tumour development through clearance and via the process of immunoediting, by which cancers will dampen the immune response to promote their progression. The advent of immunotherapies has become a revolutionary treatment as it uses the nature of the immune system to fight back at cancers. This review will focus on the pivotal role of the tumour microenvironment in tumour progression and tumour-immune dynamics, through cellular signalling, gene expression and cell-cell interactions. Subsequently, an overview of current immunotherapies will be presented and evaluated. Finally, this review will present mRNA vaccines as a novel therapeutic strategy and determine their implications for cancer treatment.
"A Review on the tumour immune microenvironment and the emergence of mRNA vaccines as a novel therapeutic strategy", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.9, Issue 1, page no.13 - 26, January-2024, Available :https://ijsdr.org/papers/IJSDR2401002.pdf
Volume 9
Issue 1,
January-2024
Pages : 13 - 26
Paper Reg. ID: IJSDR_209718
Published Paper Id: IJSDR2401002
Downloads: 000347208
Research Area: Medical Science
Country: Gurugram , Haryana , India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave