Peripheral smear and CBC findings in CAD patients:a cross-sectional study

Dr. Swathy Shanker , Dr. Afeefa Ammengara

Cardiovascular diseases, Complete blood Count, Peripheral smear

Cardiovascular diseases (CVD) are common non communicable disease and have high mortality rate globally, accounting for around 60% of all deaths. Recent studies have proved the association of various hematological parameters with cardiovascular diseases, including Red Cell Distribution Width(RDW), Mean Platelet Volume(MPV) and Neutrophil-Lymphocyte Ratio (NLR). Aim- In this study, we aim to find the alterations in RBC morphology and other Complete Blood Count (CBC) parameters in patients with Coronary Artery Diseases (CAD) by comparing the values and peripheral smear findings with that of normal population. Method- Peripheral smears and CBCs of 44 females and 56 males were reviewed from both normal population and patients with CAD, making a total of 200 cases. Blood samples were processed and evaluated by Auriba ABX Penta xlr hematology analyser. Data analysis: Data was entered and tabulated in Microsoft Excel and analyisis was carried out by SPSS software (version 16.0). Result- Among the RBC parameters compared, Mean Corpuscular Volume (MCV) showed no significant change in CAD population as compared to normal population. Other parameters showed significant difference .Among the platelet parameters reviewed, Platelet Distribution Width (PDW) showed a significant increase in CAD patients when compared to normal population. Other parameters showed insignificant change. Conclusion- According to this study, the RBC parameters have been significantly reduced in patients with CAD whereas RDW has been found to be significantly increased indicating increased anisopoikilocytosis. Higher WBC count and NLR has also been documented similar to other studies, while platelet parameters except PDW showed statistically insignificant changes.

Published Paper   E-Certificate

"Peripheral smear and CBC findings in CAD patients:a cross-sectional study", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 10, page no.307 - 312, October-2023, Available :https://ijsdr.org/papers/IJSDR2310053.pdf

Volume 8 Issue 10, October-2023

Pages : 307 - 312

Paper Reg. ID: IJSDR_208893

Published Paper Id: IJSDR2310053

Downloads: 000347302

Research Area: Life Sciences 

Country: Calicut, Kerala, India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2310053

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2310053

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

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