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Issue: May 2023

Volume 8 | Issue 5

Impact factor: 8.15

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Paper Title: The importance of herbal practice in unravelling cellular and molecular pathway of erectile dysfunction
Authors Name: Chandrasekar V , Venkatesh G , Sneha KK , Deepika R , Vanitha N
Unique Id: IJSDR2305034
Published In: Volume 8 Issue 5, May-2023
Abstract: An effective sexual encounter requires a penile erection. Majority of men experience sexual difficulties as a result of lifestyle modifications such as stress, ageing, and secondary illnesses like diabetes. There are several sexual disorders that affect men nowadays, with erectile dysfunction being a major one in all ages that affects partners' sexual lives and harms their relationships. Oral phosphodiesterase-5 inhibitors are the most common treatment for erectile dysfunction, although they are ineffective in some population with certain diseases, also lead to addiction. The formulations for increasing penile erection that are now on the market are in the form of tablets, oral jelly, suspensions, creams, gels, and sprays, however due to their subpar ADME qualities, they do not work well in all populations. In addition, a variety of illnesses, including diabetes, hypertension, atherosclerosis, stress, anxiety, depression, hypogonadism, multiple sclerosis, Parkinson's, and stroke, are the main contributors to erectile dysfunction. In these contexts, our goal is before developing a new medication, it is essential to comprehend the complete mechanism underlying penile erection which is a multiple pathological pathway and complex process. The routes involved in erectile function are summarised in this review. This review also provides information on "pharmacological treatment targets for erectile dysfunction." In addition to allopathic medications, several botanicals have a significant impact on erection and sexual behaviour. This review also provides a summary of the plants that enhance sexual behaviour and how they do so.
Keywords: Erectile dysfunction, penile erection, Nitric oxide, Rho kinase, Testosterone, Ion channels, Sirtuin, Renin angiotensin system, Central pathway, cAMP.
Cite Article: "The importance of herbal practice in unravelling cellular and molecular pathway of erectile dysfunction", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 5, page no.235 - 247, May-2023, Available :http://www.ijsdr.org/papers/IJSDR2305034.pdf
Downloads: 000222060
Publication Details: Published Paper ID: IJSDR2305034
Registration ID:206038
Published In: Volume 8 Issue 5, May-2023
DOI (Digital Object Identifier):
Page No: 235 - 247
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

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