INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Niharika Singh
, SHWETA JAISWAL , DR. AMIT KUMAR TIWARI
Unique Id:
IJSDR2304438
Published In:
Volume 8 Issue 4, April-2023
Abstract:
This review article describes the basic types of DNA damage caused by exogenous and endogenous factors, analyzes the potential consequences of each type of damage, and discusses the need for different types of DNA repair. The mechanisms by which minor damage to DNA can eventually lead to the introduction of heritable mutations are examined. The main features of the role of DNA damage in aging and carcinogenesis are outlined, and the role of iatrogenic DNA damage in human health and disease (with curative intent and as a long-term side effect of genotoxic therapies) is explained. Cells are constantly exposed to DNA damage resulting from replication or transcription, cellular metabolic activities leading to the production of DNA-damaging agents such as UV light.
Keywords:
DNA damage, DNA repair
Cite Article:
"Devices of several kinds Repair and damage to DNA", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 4, page no.2838 - 2842, April-2023, Available :http://www.ijsdr.org/papers/IJSDR2304438.pdf
Downloads:
000337071
Publication Details:
Published Paper ID: IJSDR2304438
Registration ID:205909
Published In: Volume 8 Issue 4, April-2023
DOI (Digital Object Identifier):
Page No: 2838 - 2842
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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