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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Nanosuspension: A Potential Nanosystem for Selective Drug Delivery. |
| Authors Name: | Pimple Vishal Dnyaneshwar , Patil Shraddha Udaysinh , Gonjari I.D. |
| Unique Id: | IJSDR2304293 |
| Published In: | Volume 8 Issue 4, April-2023 |
| Abstract: | The drug are classified according to BCS classification but the classes II or IV have the low solubility. The main goal of pharmaceutical research is to maximise bioavailability of these drugs for desired therapeutic efficacy, however poorly soluble drugs are constantly hindered by their unpredictable absorption patterns. Low water solubility and bioavailability are difficulties that can be solved using nanosuspension technology. All medications that are less soluble in water can benefit from nanosuspension, which belongs to a few nanometer-sized solute particles and greatly affects solubility. Precipitation, milling, high pressure homogenization, the emulsion and microemulsion method, dry co-grinding, and the supercritical fluid method are some of the several methods that have been developed to create nanosuspension. Delivery methods for nanosuspensions include oral, parenteral, pulmonary, and ocular. When included in ocular inserts and mucoadhesive hydrogels, nanosuspensions can also be employed for targeted administration of drugs. In addition to addressing the issues of low solubility and bioavailability, nanosupensions also change the pharmacokinetics of the medicine, enhancing its safety and effectiveness. |
| Keywords: | Bioavailability, BCS Class II, solubility, nanotechnology, nanosuspensions , bioavailability, Saturation solubility. |
| Cite Article: | "Nanosuspension: A Potential Nanosystem for Selective Drug Delivery.", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 4, page no.1893 - 1904, April-2023, Available :http://www.ijsdr.org/papers/IJSDR2304293.pdf |
| Downloads: | 000337212 |
| Publication Details: | Published Paper ID: IJSDR2304293 Registration ID:205372 Published In: Volume 8 Issue 4, April-2023 DOI (Digital Object Identifier): Page No: 1893 - 1904 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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