INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
The objective of present investigation was to evaluate Lepidium sativum, Isapgol mucilage as a suspending agent, compare this with suspension prepare by using NaCMC as a suspending agent and marketed Ibuprofen suspension(100mg/5ml), and the effect of mucilage concentration on in vitro dissolution rate of Ibuprofen. Suspensions were prepared by using sodium carboxymethyl cellulose powder and different mucilage at different concentration (0.1%,0.2%,0.3%,0.4%,0.5%w/v). Suspension were evaluated for pH, sedimentation volume (F), density, drug content , viscosity measurement, In vitro dissolution study, FTIR and stability study. The all formulation showed more than 90% drug release over a period of 60 minutes. The suspensions were found to be stable during the study periods. There was no any change in color, odor and taste was observed. The drug content in all the suspensions was found to be within the limit.
"Formulation and Evaluation of Ibuprofen Suspension By Using Different Natural Suspending Agent.", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 4, page no.1841 - 1860, April-2023, Available :http://www.ijsdr.org/papers/IJSDR2304286.pdf
Downloads:
000337070
Publication Details:
Published Paper ID: IJSDR2304286
Registration ID:205595
Published In: Volume 8 Issue 4, April-2023
DOI (Digital Object Identifier):
Page No: 1841 - 1860
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
Facebook Twitter Instagram LinkedIn