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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | A REVIEW ON EXTRACTION AND EVALUATION OF IN VITRO ANTHELMINTIC ACTIVITY USING MOMORDICA CHARANTIA (BITTER GOURD) |
| Authors Name: | Dr. S. Sandhya Rani , M. Prashanth , E. Uday Kumar , G. Lalitha Hiranmai , R. Lokhiya Nayak |
| Unique Id: | IJSDR2304284 |
| Published In: | Volume 8 Issue 4, April-2023 |
| Abstract: | Momordica charantia (Family: Cucurbit ales), as known as bitter melon or gourd, is a daily consumption as food and traditional medicinal plant in Southeast Asia and Indo-China. It has been shown to possess anticancer, antidepressant, antidiabetic, anti-inflammatory, antimicrobial, ant obesity, antioxidant, and antiulcer properties. It is also used for the treatment of many ailments such as abortifacient, contraceptive, dysmenorrhoea, eczema, emmenagogue, antimalarial, galactagogue, gout, jaundice, abdominal pain, kidney stone, laxative, leprosy, leucorrhoea, piles, pneumonia, psoriasis, purgative, rheumatism, fever and scabies. The present work aims at evaluation of anthelmintic property of M. charantia seeds extracts against Indian adult earthworm Pheretima posthuman, Stellantchasmus falcatus. Albendazole was used as the standard drug. Petroleum ether, chloroform, ethanol and aqueous extracts at concentration of 40 mg/mL each were evaluated for anthelmintic activity. The time taken for paralysis and death of each worm were determined. Among chloroform ethanol, aqueous, and petroleum ether extract the extracts chloroform extract showed best anthelmintic activity by inducing paralysis within 3 min and death within 8 min. This shows the better anthelmintic activity when compared to standard drug. |
| Keywords: | Anthelmintic activity, Bitter gourd, Extraction, Earthworms |
| Cite Article: | " A REVIEW ON EXTRACTION AND EVALUATION OF IN VITRO ANTHELMINTIC ACTIVITY USING MOMORDICA CHARANTIA (BITTER GOURD)", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 4, page no.1828 - 1833, April-2023, Available :http://www.ijsdr.org/papers/IJSDR2304284.pdf |
| Downloads: | 000337074 |
| Publication Details: | Published Paper ID: IJSDR2304284 Registration ID:205442 Published In: Volume 8 Issue 4, April-2023 DOI (Digital Object Identifier): Page No: 1828 - 1833 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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