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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Esmolol and Dexmedetomedine to Attenuate Cardiovascular responses to tracheal extubation in patient undergoing elective surgeries under general anaesthesia:A comparative double blind randomized trial |
| Authors Name: | Dr.Anubh gupta , Dr.Sultana Parbin Ahmed , Dr.Angshuman Kalita , Dr.Satish hanse , Dr.Sharmistha sharma |
| Unique Id: | IJSDR2304240 |
| Published In: | Volume 8 Issue 4, April-2023 |
| Abstract: | Abstract Background: Tracheal extubation in patients under general anaesthesia is done at the end of the surgery. Extubation is often accompanied by unpredictable and variable haemodynamic changes and respiratory tract complications. Dexmedetomidine, a selective α2 adrenoreceptoragonist,and Esmolol a selective beta 1 blocker is compared in this study to know which will more effective in reducing the stress of extubation in patients undergoing general anaesthesia. Material and methods: This study was a double blind randomized trial conducted in department of anaesthesia and critical care, Tezpur medical college and hospital, Tezpur. A total of 70(seventy) patient were selected and divided into two groups A and B 35 each. Group A patients received intravenous Esmolol hydrochloride 1.5 mg/kg diluted with 0.9% normal saline to 10 ml and Group B patients received intravenous Dexmedetomidine Hcl 0.5 μg/kg diluted with 0.9% normal saline to 10 ml over 15 minutes before anticipated time of end of surgery.Anaesthsia technique were standardised. Heart rate,systolic,diastolic,mean arterial blood pressure were recorded and was compared among proposed groups. Results: In this study it was found that heamodynamic changes during extubatation was better tolerated by group B patients than group A patients. Conclusion:From this study it was concluded that Dexmetomedine facilitates more smooth extubation than Esmolol in patient undergoing surgery under general anaesthesia. |
| Keywords: | α2 adrenoreceptoragonist, Dexmedetomidine, extubation, heamodynamic |
| Cite Article: | "Esmolol and Dexmedetomedine to Attenuate Cardiovascular responses to tracheal extubation in patient undergoing elective surgeries under general anaesthesia:A comparative double blind randomized trial", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 4, page no.1500 - 1506, April-2023, Available :http://www.ijsdr.org/papers/IJSDR2304240.pdf |
| Downloads: | 000337071 |
| Publication Details: | Published Paper ID: IJSDR2304240 Registration ID:205356 Published In: Volume 8 Issue 4, April-2023 DOI (Digital Object Identifier): Page No: 1500 - 1506 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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