INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
SPECTRUM OF FUNGI IN COVID-19 ASSOCIATED MUCORMYCOSIS IN A TERTIARY CARE HOSPITAL, SOUTH INDIA.
Authors Name:
C. Divya Teja
, B. Praveena , S. Nawaz Sharif , S. Sumanjali , G. Swarna Latha
Unique Id:
IJSDR2304192
Published In:
Volume 8 Issue 4, April-2023
Abstract:
Background: Coronavirus disease (COVID-19) causes an immunosuppressed state and increases risk of secondary infections like mucormycosis. We studied the predisposing factors, diagnosis and isolated most common fungi causing mucormycosis among patients with COVID-19 infection. The aim of this study is to report the spectrum of fungi, causing Mucormycosis in RT-PCR positive COVID-19 patients, cultured on SDA and study the role of other factors responsible for the disease. Methodology: A prospective, observational study on Mucormycosis in RT-PCR positive COVID-19 patients based on hospital records and fungal culture reports from 12th May 2021 to 21st July 2021. The study includes cultures conducted on Nasal debridement samples from patients admitted in the hospital with RT- PCR confirmed COVID-19 and typical symptoms of Mucormycosis. Results: The mean age of the COVID-19 confirmed patients from whom Nasal debridement samples were collected was 52 years. Among the study group, 66% were Male and 89% among them had known history of Diabetes. The Mean time interval between the onset of COVID-19 disease and the diagnosis of Mucormycosis was 7 days (Range 1-37 days) in the study group. Out of 341 samples received and cultured on SDA, 85 samples (24.92%) were positive for Mucormycosis. Out of 85 samples 69 (81.17%) belong to the family mucoraceae of which 57 (82.60%) are of Rhizopus species, 8(11.59%) belonged to mucor species, 3 (4.34%) belonged Lichthemia and 1(1.14%) belonged to Rhizomucor species. The remaining 16 (18.83%) doesn’t belong to the mucoraceae family. Among the non- mucoraceae, 7 (43.75%) are Aspergillus niger, 4(25%) were Aspergillus fumigatus, 3(19.75%) were Aspergillus flavus and 2(12.5%) belonged to Trichophyton species. Conclusion: Patients of Mean age 56 years with known diabetes status hospitalized for Covid-19 are at higher risk of developing Mucormycosis with the most common causative organism isolated being Rhizopus species.
"SPECTRUM OF FUNGI IN COVID-19 ASSOCIATED MUCORMYCOSIS IN A TERTIARY CARE HOSPITAL, SOUTH INDIA.", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 4, page no.1168 - 1171, April-2023, Available :http://www.ijsdr.org/papers/IJSDR2304192.pdf
Downloads:
000337077
Publication Details:
Published Paper ID: IJSDR2304192
Registration ID:203460
Published In: Volume 8 Issue 4, April-2023
DOI (Digital Object Identifier):
Page No: 1168 - 1171
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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