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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | SEROPREVALENCE OF HIV AND HEPATITIS C INFECTION AMONG BLOOD DONORS IN CENTRAL INDIA: A STUDY OF 8 YEARS IN TERTIARY CARE CENTRE IN GWALIOR, MADHYA PRADESH, INDIA |
| Authors Name: | Reema Bhushan , Prakriti Gupta , Sudha Iyengar , Harshvardhan Gupta , Prem Chouhan |
| Unique Id: | IJSDR2304112 |
| Published In: | Volume 8 Issue 4, April-2023 |
| Abstract: | INTRODUCTION: The prevalence of HIV and HCV infection varies worldwide. The risk of contracting HIV infection from transfusion of a unit of infected blood is estimated to be over 95%. The HIV prevalence among the blood donors around the world varies with an average of around 0.1%. The seroprevalence rate of HCV among the blood donors in India is estimated to be around 0.53 to 5.1%. National AIDS Control organization (NACO) mandates to screen every unit of blood for HIV and HCV. Aim of this study was to estimate the seroprevalence of HIV and HCV among the voluntary and replacement donors over a period of 8 years at a tertiary care hospital in Gwalior. MATERIALS AND METHODS: All the donors which were found fit after screening by trained personnel, after satisfactory answering the donor’s questionnaire, their physical examination and hemoglobin (Hb %) estimation were included in the study. A total of 160629 blood units from the selected donors were collected during the period of 8 years (2015-2022) with voluntary donors and replacement donors. Three ml blood in plain vial and 2 ml blood in EDTA (ethylene diamine tetra acetic acid) vial taken from the satellite bag. All samples were screened for HIV, HCV and other TTIs. Tests for HIV and HCV were performed with commercially available enzyme immune assay kit and rapid cards. RESULTS: Major contribution in blood donation was from male donors (94.7%). Majority of donation was done voluntarily (88.4 %). Out of the total 160629 donors tested for TTIs over 8 years, 146 (0.09%) donors were positive for HIV (p <0.05) and 193 (0.12%) donors were positive for anti HCV (p<0.05). There was increase in blood donation from voluntary category from 2015-2022 with a decreasing trend of HIV and HCV positivity from 2015 to 2022. CONCLUSION: There was a decreasing trend of HIV and HCV positivity from 2015-2022. Since, no vaccine is presently available for immunization against HIV and HCV infection, transfusion transmitted HIV and HCV remains a potential threat to the safety of the blood supply. |
| Keywords: | Voluntary, Replacement |
| Cite Article: | "SEROPREVALENCE OF HIV AND HEPATITIS C INFECTION AMONG BLOOD DONORS IN CENTRAL INDIA: A STUDY OF 8 YEARS IN TERTIARY CARE CENTRE IN GWALIOR, MADHYA PRADESH, INDIA ", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 4, page no.613 - 616, April-2023, Available :http://www.ijsdr.org/papers/IJSDR2304112.pdf |
| Downloads: | 000337211 |
| Publication Details: | Published Paper ID: IJSDR2304112 Registration ID:205144 Published In: Volume 8 Issue 4, April-2023 DOI (Digital Object Identifier): Page No: 613 - 616 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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