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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | PLASMA EXCHANGE A NEWER THERAPEUTIC APPROACH |
| Authors Name: | Dr. Neha Gupta , Dr. Vishal Gupta |
| Unique Id: | IJSDR2302145 |
| Published In: | Volume 8 Issue 2, February-2023 |
| Abstract: | Introduction: Plasma exchange is a therapeutic procedure used to treat a variety of diseases through the bulk removal of plasma. THERAPEUTIC PLASMA EXCHANGE (TPE) is a potentially lifesaving but also invasive procedure with risk of adverse events and complications and requires close monitoring by experienced teams. We present our experience with TPE in treatment of various neurologic and non-neurologic diseases. Aim: To evaluate TPE as primary therapy or as a first-line adjunct to other initial therapies as mentioned by American Society for Apheresis (ASFA). Materials and Methods: A retrospective analysis of TPE procedures was done for a period of Three years, from January 2018 to December 2020 in a tertiary care hospital. A total of 78 TPE procedures were performed in 22 patients between 2 to 75 years of age. Clinical and laboratory investigations like ECG, chest X-ray, cardiorespiratory status and serology were carried out before the TPE procedure. Results: A total of 22 patients were enrolled in the present study. Guillain-Barre Syndrome (GBS) (68.18%, n=15) was the main indication for TPE, followed by Myasthenia Gravis (MG) (13.63%, n=3). Overall incidence of adverse reactions was 9.09%, inadequate vascular access was a common complication encountered in pediatric age group. Conclusion: Our results show that TPE is not only safe and effective treatment alternative to Intravenous Immunoglobulin (IVIG), it also strongly holds evidence in the improvement of neurological disorders compared to non-neurological disorders. There is need of further detail evaluation on large number of cases for proper evidence based practice |
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| Cite Article: | "PLASMA EXCHANGE A NEWER THERAPEUTIC APPROACH ", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 2, page no.842 - 846, February-2023, Available :http://www.ijsdr.org/papers/IJSDR2302145.pdf |
| Downloads: | 000337209 |
| Publication Details: | Published Paper ID: IJSDR2302145 Registration ID:204173 Published In: Volume 8 Issue 2, February-2023 DOI (Digital Object Identifier): Page No: 842 - 846 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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