INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
ABSTRACT Background Prostate cancer is a hormone-dependent malignancy with slow progression. Biopsy for histopathology of samples enables us to assert the diagnosis. Prostate biopsies are usually performed by the interventional radiologist in the office setting using a transrectal probe. The current standard of care involves obtaining 10-14 cores from different anatomical sections. These biopsies are usually not directed into a specific lesion as most prostate cancers are not visible on TRUS. Magnetic resonance imaging (MRI)-guided prostate biopsy has a higher sensitivity than the ultrasound-guided biopsy, but its realization requires a dedicated interventional MRI, specific material, which is not available in our context; hence, ultrasound-guided biopsy remains of great interest. Presently, ultrasound-guided biopsy is the gold standard for diagnosis of prostate cancer, outside of a clinical trial. The objective of our work is to evaluate our practice of transrectal ultrasound-guided prostate biopsy using an endorectal probe by assessing the indications, describing the technique and evaluating the morbidity and histology results. Methods This is a descriptive study of ultrasound-guided prostate biopsies performed over a 2-year period. The parameters evaluated were age, rectal examination findings, total PSA level, frequency of the procedure, prostate biopsy morbidities and results. Descriptive statistics were performed, and comparison of qualitative variables was made by the chi-square test with statistical significance set for P≥0.0001 Results One hundred and fifty-six patients were included over a two-year period. The mean age of our patients was 63.5. Rectal examination finding was suspicious in 37.2% and the median total PSA was 11.2ng/ml (0.1 – 121ng/ml). 99.3% of patients reported their pathology results. Prostatic adenocarcinoma was the most common finding accounting for 38.7% of results. Complications were observed in 11 patients (7%) with a predominance of initial hematuria, dysuria and rectal pain. The frequency of more than one procedure was 1.3%. Conclusion In our series, the cancer detection rate was significant and the complications rate was acceptable at 7%.
"ULTRASOUND-GUIDED PROSTATE BIOPSY: INDICATIONS, MORBIDITY AND OUTCOME AT UNIVERSITY OF UYO TEACHING HOSPITAL.", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.8, Issue 2, page no.420 - 425, February-2023, Available :http://www.ijsdr.org/papers/IJSDR2302070.pdf
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Publication Details:
Published Paper ID: IJSDR2302070
Registration ID:203957
Published In: Volume 8 Issue 2, February-2023
DOI (Digital Object Identifier):
Page No: 420 - 425
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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