FORMULATION AND EVALUATION OF PHARMACEUTICAL AQUEOUS GEL OF CITRUS AURANTIUM DULCIS (ORANGE) PEELS EXTRACT FOR MOUTH ULCER TREATMENT

Manthan M. Thawkar , Maroti M, Jeurkar , Rajashree V. Lode , Satish B. Kosalge

Mouth ulcer gel, Orange, Antimicrobial activity, Antiulcer activity, citrus aurantium dulcis.

The objectives of present investigation were to formulate and evaluate herbal gel for mouth ulcer treatment of dried powdered citrus aurantium dulcis (orange) peels extract. Herbal gel was prepared by using different concentration of powdered citrus aurantium dulcis and carbopol 934, propylene glycol as a gel base. Formulations were evaluated for various physical parameters. The formulated gel was transparent, homogeneous and had PH ranges from 7 to 7.5.Also this formulation showed acceptable rheological behavior with applicable spread ability and extrudability properties. Antimicrobial studies of gel showed excellent efficacy against staphylococcus aureus and Escherichia coli. From the experimental evidence of in-vitrostudies it was observed that powdered contain flavonoids so it showed significant antioxidantand antimicrobial activity. This herbal aqueous gel formulation was stable, safe and effective for the treatment of mouth ulcer.

Published Paper   E-Certificate

"FORMULATION AND EVALUATION OF PHARMACEUTICAL AQUEOUS GEL OF CITRUS AURANTIUM DULCIS (ORANGE) PEELS EXTRACT FOR MOUTH ULCER TREATMENT", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 1, page no.1215 - 1218, January-2023, Available :https://ijsdr.org/papers/IJSDR2301193.pdf

Volume 8 Issue 1, January-2023

Pages : 1215 - 1218

Paper Reg. ID: IJSDR_203777

Published Paper Id: IJSDR2301193

Downloads: 000347320

Research Area: Pharmacy

Country: Nagpur , Maharastra , India

Published Paper PDF: https://ijsdr.org/papers/IJSDR2301193

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2301193

DOI: http://doi.one/10.1729/Journal.32957

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: IJSDR(IJ Publication) Janvi Wave

This work is licensed under a Creative Commons Attribution 4.0 International License and The Open Definition