A Cross Sectional Study On Diagnostic Findings And Treatment Between Children And Adults Based On KDIGO Guidelines Of Nephrotic Syndrome
Dr. K. Krupa Jacinth*
, B.Heena , G.Supriya , M.Renuka , N.Mounica
Key Words: KDIGO, Nephrotic syndrome, MCD, FSGS, PPI, Department of pharmacy practice, CESCOP.
Aim and objectives: The aim of our study is, to study the clinical profile, investigation profile and treatment plan in children and adults with nephrotic syndrome according to KDIGO GUIDELINES. Methods: This is a Prospective Observational Study and the subjects involved are the patients visiting a pediatric department and nephrology department, diagnosed with a nephrotic syndrome and with relapses. All the data of the subjects are collected by using the case proforma and the data collection includes demographic details, past medical history, past medication history, history investigations, personal habits, allergies, diagnosis, laboratory investigations and drug prescribed. Results: In our study a total of 99 subjects were recruited among those paediatrics were 45 and adults were 54. On biochemical examination the sr. albumin profile shows hypoalbuminemia the major hypoalbuminemia range is found among paediatrics N=45 with mean of 15 ie., >0.6mg/dl- 37(82.2%), followed by 0.2-0.6mg/dl -7 (15.5%), <0.2mg/dl-1 (2.2%) and adults N=54 with mean of 18 major hypoalbuminemia found at >0.6mg/dl -39(72.2%), followed by 0.2-0.6mg/dl-13 (24%), and <0.2-2 (3.7%) On urine examination frothy appearance of urine was observed in almost patients of paediatrics and adults. Main treatment includes managing edema: Lasix; hypertension: nefidipine, enalapril, amlodipine, betablockers, telmisartan; corticosteroid therapy: tab.prednisolone, inj.methyl prednisolone; immunosuppressant: methotrexate, sulfasalazine, hydroxychloroquine, azathioprine; antibiotics: ceftriaxone, doxycycline, amoxyclav, other antibiotics; alkalysing agent: sodium bicarbonate; antacids: ranitidine;PPIs: pantoprazole. Conclusion:- Our study concluded that, most of the children are with minimal change disease but in adults none were observed with MCD .Most of the adults are diagnosed with secondary cause (FSGS).In adults mostly in females lupus nephritis were observed .Hypertension is one of the complication mostly seen in pediatrics.
"A Cross Sectional Study On Diagnostic Findings And Treatment Between Children And Adults Based On KDIGO Guidelines Of Nephrotic Syndrome", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 1, page no.1163 - 1179, January-2023, Available :https://ijsdr.org/papers/IJSDR2301185.pdf
Volume 8
Issue 1,
January-2023
Pages : 1163 - 1179
Paper Reg. ID: IJSDR_203741
Published Paper Id: IJSDR2301185
Downloads: 000347183
Research Area: Pharmacy
Country: Kurnool District, Andhra Pradesh, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
