Antioxidant and Antidiabetic Activity of Phyllanthus Emblica Fruit Extract in Wistar Rats

S. ANITHA KUMARI , P. MADHUSUDHANACHARY

Phyllanthus emblica, Rats, antioxidant, antidiabetic

The present study was performed to assess the antioxidant and antidiabetic activity of Phyllanthus emblica fruit extract. The antioxidant activity was carried out in different concentrations of aqueous fruit extract using DPPH assay. The aqueous fruit extract of Phyllanthus emblica exhibited more scavenging activity of DPPH in a dose-dependent manner when compared to the control. The antidiabetic activity of Phyllanthus emblica fruit extract was studied in male wistar rats. The rats were divided into 5 groups. Group I served as the control group. Group II was rendered diabetic through intraperitoneal injection of streptozotocin (60mg/Kg body weight) .Group III received aqueous fruit extract of Phyllanthus emblica (200mg/kg body weight) daily through oral gavage for 28 days. Group IV rats received glibenclamide (600µg/Kg body weight) daily through oral gavage for 28 days and group V received only the aqueous fruit extract of Phyllanthus emblica. The study revealed a significant increase in the blood glucose levels and a decrease in the plasma insulin levels in the diabetic rats when compared to the control rats indicating the antidiabetic activity of Phyllanthus emblica fruit extract. The study suggests that Phyllanthus emblica fruit extract can be recommended for use as a natural supplementary herbal remedy to the diabetic patients.

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"Antioxidant and Antidiabetic Activity of Phyllanthus Emblica Fruit Extract in Wistar Rats", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.8, Issue 1, page no.1005 - 1009, January-2023, Available :https://ijsdr.org/papers/IJSDR2301160.pdf

Volume 8 Issue 1, January-2023

Pages : 1005 - 1009

Paper Reg. ID: IJSDR_203520

Published Paper Id: IJSDR2301160

Downloads: 000347170

Research Area: Other

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Published Paper PDF: https://ijsdr.org/papers/IJSDR2301160

Published Paper URL: https://ijsdr.org/viewpaperforall?paper=IJSDR2301160

ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016

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