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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | CLINICAL PROFILING OF CHIKUNGUNYA POSITIVE PATIENTS BY RTPCR IN TERTIARY CARE CENTER,PUNE |
| Authors Name: | Dr.Neha Bagade , Dr.Suvarna Joshi , Dr.Rajesh Karyakarte |
| Unique Id: | IJSDR2212131 |
| Published In: | Volume 7 Issue 12, December-2022 |
| Abstract: | Introduction -Chikungunya is a public health problem in Asian,African and Latin American countries.The clinical differentiation of Chikungunya from dengue is very difficult as both diseases share similar clinical signs and symptoms leading to misdiagnosis of Chikungunya in areas where dengue is endemic. Aims and objectives -1)To determine the clinical profiling of IgM ELISA/RTPCR positive patients.2)To determine the distribution of patients diagnosed by RTPCR and ELISA Method-Purposive sampling Result-Out of 1405,320 showed presence of Chikungunya IgM antibodies.Among these 260/320 (81.25%) were Chikungunya positive alone while 60/320(14.6%) showed presence of both dengue and Chikungunya IgM antibodies indicating co-infection.90 patients were having fever <5 days among this 16(17.7%) positive by IgM ELISA and among this 10(62.5%) show PCR positive and 6(37.5%) PCR megative. Discussion -Total 90 patients were tested by RTPCR out of which 55(61.1%) were chikungunya positive.In contrast Philipee Renault et al in their study mentioned 6.17% case detection by RTPCR.In Jean Paul Carrera et al who reported that 44.7% Chikungunya cases detected by RTPCR. Conclusion – The rate of positivity by RTPCR was highest in acute phase first 5 days indicates definitive diagnosis in very early stages. |
| Keywords: | Keywords -Chikungunya,Dengue, co-infection, RTPCR,ELISA |
| Cite Article: | "CLINICAL PROFILING OF CHIKUNGUNYA POSITIVE PATIENTS BY RTPCR IN TERTIARY CARE CENTER,PUNE", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 12, page no.847 - 859, December-2022, Available :http://www.ijsdr.org/papers/IJSDR2212131.pdf |
| Downloads: | 000314594 |
| Publication Details: | Published Paper ID: IJSDR2212131 Registration ID:203173 Published In: Volume 7 Issue 12, December-2022 DOI (Digital Object Identifier): Page No: 847 - 859 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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