INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Factorial design was used to develop and validate the HPLC method for valsartan nanoparticle determination
Authors Name:
PISINI KRISHNA PRASAD
Unique Id:
IJSDR2210098
Published In:
Volume 7 Issue 10, October-2022
Abstract:
Abstract According to the ICH guidelines, a high performance liquid chromatographic technique was devised, optimised, and validated. In this investigation, the mobile phase for the measurement of valsartan was composed of 20 mM ammonium formate and acetonitrile in a 57:43 ratio. The influence of variable components was optimised using a full factorial design. Peak area, tailing factor, and number of theoretical plates were the answers. On peak area, the quadratic effects of flow rate and wavelength both separately and in combination were most significant (p 0.0001 and p 0.0086, respectively); the
Keywords:
KEYWORDS: Nanoparticles; HPLC; Valsartan; Full Factorial Designs
Cite Article:
"Factorial design was used to develop and validate the HPLC method for valsartan nanoparticle determination ", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 10, page no.603 - 606, October-2022, Available :http://www.ijsdr.org/papers/IJSDR2210098.pdf
Downloads:
000337070
Publication Details:
Published Paper ID: IJSDR2210098
Registration ID:202186
Published In: Volume 7 Issue 10, October-2022
DOI (Digital Object Identifier):
Page No: 603 - 606
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
Facebook Twitter Instagram LinkedIn