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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH
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ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
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Paper Title:	Catalase function in age-related degenerative diseases
Authors Name:	Anju Ahlawat , Soniya Jangra , Heena
Unique Id:	IJSDR2210053
Published In:	Volume 7 Issue 10, October-2022
Abstract:	Cellular macromolecules such as nucleic acids, proteins, and lipids can chemically react with reactive oxygen species (ROS) created in the cell during normal metabolic processes. Later oxidative changes could alter their chemical compositions and harm their biological functions. Fortunately, cells have developed several antioxidant defense mechanisms (such as metabolites, vitamins, and enzymes). One of the essential antioxidant enzymes, catalase, decomposes cellular hydrogen peroxide to create water and oxygen, reducing oxidative stress to a significant extent. Catalase deficiency influences the pathophysiology of several age related degenerative disorders. Later include diabetes mellitus, hypertension, anemia, vitiligo, Parkinson's disease, and bipolar disorder. As a result, numerous laboratories are attempting to investigate its potential as a medicine for treating such disorders. This review discusses the direct and indirect roles of catalase deficiency or modification in developing certain severe diseases, including Vitiligo, Parkinson's disease, Alzheimer's disease, and Diabetes mellitus.
Keywords:	Degenrative disease, Anti-oxidant enzyme, Aging, Catalase, Oxidative damage
Cite Article:	"Catalase function in age-related degenerative diseases", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 10, page no.297 - 301, October-2022, Available :http://www.ijsdr.org/papers/IJSDR2210053.pdf
Downloads:	000337077
Publication Details:	Published Paper ID: IJSDR2210053 Registration ID:201988 Published In: Volume 7 Issue 10, October-2022 DOI (Digital Object Identifier): Page No: 297 - 301 Publisher: IJSDR \| www.ijsdr.org ISSN Number: 2455-2631

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