INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Sodium borohydride - Copper (II) acetyl acetonate: a ‘Greener’ approach to reduction of Aromatic Nitro substrates
Authors Name:
Sreela Dasgupta
, Akshay Parab
Unique Id:
IJSDR2209176
Published In:
Volume 7 Issue 9, September-2022
Abstract:
The formation of amines through the reduction of the nitro functional group represents a fundamental transformation which is versatile in its being the synthesis of choice for a wide variety of organic molecules in diverse fields. New synthetic strategies for complex polyfunctional molecules have always presented a challenge in having to fulfill diverse criteria such as being highly efficient and selective concurrently, besides being ‘green’ and ‘environment friendly’. Hence although a plethora of methodologies are available in literature effecting this transformation, the quest for a method which is superior to the existing ones, will always post a challenge to the chemist. The present research work studies the use of sodium borohydride, a relatively mild and selective reducing agent, for bringing about this transformation in the presence of an inorganic complex. The method explores the viability of the reagent with aromatic substrates, both with electron donating as well as electron withdrawing substituents. The explored technique is also ‘green’ in being carried out in benign solvents such as water or aqueous ethanol.
Keywords:
Sodium borohydride, copper (II) acetyl acetonate, nitro, amine, reduction
Cite Article:
"Sodium borohydride - Copper (II) acetyl acetonate: a ‘Greener’ approach to reduction of Aromatic Nitro substrates", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 9, page no.1103 - 1105, September-2022, Available :http://www.ijsdr.org/papers/IJSDR2209176.pdf
Downloads:
000336256
Publication Details:
Published Paper ID: IJSDR2209176
Registration ID:201912
Published In: Volume 7 Issue 9, September-2022
DOI (Digital Object Identifier):
Page No: 1103 - 1105
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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