Sodium borohydride - Copper (II) acetyl acetonate: a ‘Greener’ approach to reduction of Aromatic Nitro substrates
Sreela Dasgupta
, Akshay Parab
Sodium borohydride, copper (II) acetyl acetonate, nitro, amine, reduction
The formation of amines through the reduction of the nitro functional group represents a fundamental transformation which is versatile in its being the synthesis of choice for a wide variety of organic molecules in diverse fields. New synthetic strategies for complex polyfunctional molecules have always presented a challenge in having to fulfill diverse criteria such as being highly efficient and selective concurrently, besides being ‘green’ and ‘environment friendly’. Hence although a plethora of methodologies are available in literature effecting this transformation, the quest for a method which is superior to the existing ones, will always post a challenge to the chemist. The present research work studies the use of sodium borohydride, a relatively mild and selective reducing agent, for bringing about this transformation in the presence of an inorganic complex. The method explores the viability of the reagent with aromatic substrates, both with electron donating as well as electron withdrawing substituents. The explored technique is also ‘green’ in being carried out in benign solvents such as water or aqueous ethanol.
"Sodium borohydride - Copper (II) acetyl acetonate: a ‘Greener’ approach to reduction of Aromatic Nitro substrates", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.7, Issue 9, page no.1103 - 1105, September-2022, Available :https://ijsdr.org/papers/IJSDR2209176.pdf
Volume 7
Issue 9,
September-2022
Pages : 1103 - 1105
Paper Reg. ID: IJSDR_201912
Published Paper Id: IJSDR2209176
Downloads: 000347187
Research Area: Chemistry
Country: Mumbai, Maharashtra, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
