Molecular docking studies of lupeol and beta-sitosterol on Immunomodulatory receptors: Research
Ishwari Hemant Sidwadkar
, Dr. N. S. Naikwade , Rutuja Nandkumar Mali , Nikhil Dilip More , Dhiraj Jalindhar Pawar
immunomodulator.lupeol, beta-sitosterol, Toll like receptors, TNF-α.
Abstract- The objective of present work was to study the immunomodulatory potential of lupeol and beta-sitosterol by in silico approach. In silico models involved to study binding affinity of lupeol and beta-sitosterol molecules on immune modified proteins such as Toll like receptor and human tumor necrosis factor-alpha (TNF-α). Docking results showed that the lupeol and beta-sitosterol bioactive molecules were showed immune modulatory activity due to high binding affinity and H bonding interaction with active sites of Toll like receptors and TNF-α respectively as compared to standard immunomodulatory molecule levamisole. Based on docking lupeol and beta-sitosterol were concluded as immunomodulatory potential candidate.
"Molecular docking studies of lupeol and beta-sitosterol on Immunomodulatory receptors: Research", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.7, Issue 9, page no.825 - 828, September-2022, Available :https://ijsdr.org/papers/IJSDR2209131.pdf
Volume 7
Issue 9,
September-2022
Pages : 825 - 828
Paper Reg. ID: IJSDR_201874
Published Paper Id: IJSDR2209131
Downloads: 000347252
Research Area: Pharmacy
Country: sangli, maharashtra, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
