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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Role of Amylin Analogues in Diabetes mellitus: A Review |
| Authors Name: | BHARTI KAILAS WARKHADE , SANYUJA SATISH NIKAM , GEETANJALI LAXMAN KADAM , RITA DADASAHEB CHAKOLE , MANOJ SHRAVAN CHARDE |
| Unique Id: | IJSDR2209076 |
| Published In: | Volume 7 Issue 9, September-2022 |
| Abstract: | Diabetes mellitus is hyperglycemic condition that occurs due to defects in insulin secretion or β-cell destruction. Amylin is an 37-amino acid peptide co synthesized and co secreted with insulin which is firstly isolated, purified, and characterized from the amyloid deposits in the pancreases of type 2 diabetics patients. Amylin deficiency occurs in type I and late stage type II diabetes patients due to β-cell destruction. Pramlintide (Symlin®), is an synthetic analogue of the naturally occurring pancreatic hormone amylin, is currently used with insulin in adjunctive therapy for type 1 and type 2 diabetes mellitus. Several synthetic approaches are uesd for synthesis of pramlitide via microwave irradiation. Amylin agonists could also be useful for weight loss, especially in combination with other agents. |
| Keywords: | Diabetes Mellitus, Amylin Analogues, Co-secreted with, Pramlintide. |
| Cite Article: | "Role of Amylin Analogues in Diabetes mellitus: A Review", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 9, page no.449 - 453, September-2022, Available :http://www.ijsdr.org/papers/IJSDR2209076.pdf |
| Downloads: | 000337067 |
| Publication Details: | Published Paper ID: IJSDR2209076 Registration ID:201655 Published In: Volume 7 Issue 9, September-2022 DOI (Digital Object Identifier): Page No: 449 - 453 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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