Role of Amylin Analogues in Diabetes mellitus: A Review
BHARTI KAILAS WARKHADE
, SANYUJA SATISH NIKAM , GEETANJALI LAXMAN KADAM , RITA DADASAHEB CHAKOLE , MANOJ SHRAVAN CHARDE
Diabetes Mellitus, Amylin Analogues, Co-secreted with, Pramlintide.
Diabetes mellitus is hyperglycemic condition that occurs due to defects in insulin secretion or β-cell destruction. Amylin is an 37-amino acid peptide co synthesized and co secreted with insulin which is firstly isolated, purified, and characterized from the amyloid deposits in the pancreases of type 2 diabetics patients. Amylin deficiency occurs in type I and late stage type II diabetes patients due to β-cell destruction. Pramlintide (Symlin®), is an synthetic analogue of the naturally occurring pancreatic hormone amylin, is currently used with insulin in adjunctive therapy for type 1 and type 2 diabetes mellitus. Several synthetic approaches are uesd for synthesis of pramlitide via microwave irradiation. Amylin agonists could also be useful for weight loss, especially in combination with other agents.
"Role of Amylin Analogues in Diabetes mellitus: A Review", IJSDR - International Journal of Scientific Development and Research (www.IJSDR.org), ISSN:2455-2631, Vol.7, Issue 9, page no.449 - 453, September-2022, Available :https://ijsdr.org/papers/IJSDR2209076.pdf
Volume 7
Issue 9,
September-2022
Pages : 449 - 453
Paper Reg. ID: IJSDR_201655
Published Paper Id: IJSDR2209076
Downloads: 000347240
Research Area: Pharmacy
Country: karad, SATARA, Maharashtra, India
ISSN: 2455-2631 | IMPACT FACTOR: 9.15 Calculated By Google Scholar | ESTD YEAR: 2016
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.15 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: IJSDR(IJ Publication) Janvi Wave
