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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Immersion of lower limbs in water; Effects of selected heavy metals on testosterone secretion in adult male subjects. |
| Authors Name: | Okpala C. , Ufearo C. S. |
| Unique Id: | IJSDR2208119 |
| Published In: | Volume 7 Issue 8, August-2022 |
| Abstract: | People have contact with body of different types of water for different reasons (Swimming, fishing, off-shore workers, drinking, bathing etc.) they stay in water for several minutes to hours daily. Some of these waters contain heavy metals. This may have an effect which may have been ignored based on its insignificant level or based on the understanding that the skin barrier (corneal layer) prevents entry of foreign materials into the body. This research tends to find the effects of selected heavy metals on testosterone secretion in adult male subjects during immersion of lower limb in water. 33 male students from Nnamdi Azikiwe University College of Health Sciences were recruited for the study. Ethical clearance was obtained from the faculty ethical committee. The volunteers were divided into three groups (A[marine water], B[fresh water], C[distilled water]) and were asked to immerse their lower limb in different water type according to their group for one hour every day for fifteen days. Blood samples were collected (before and after immersion) from the volunteers intravenously on 1st, 5th, 10th and 15th day. The levels of testosterone were measured by ELISA methods. The mean difference of data collected before and after immersion was established. Data obtained were compared with control group using student T-test method, P<0.05. Those exposed to marine water showed a negative response in plasma testosterone concentration. There are significant difference in plasma testosterone level between groupA and groupC on Day0 and groupA and groupC on Day10. According to the research result, it could be suggested that exposure to heavy metals in water by immersion of lower limb could attenuate testosterone secretion in adult males; the mechanism of action for this effect is poorly understood. |
| Keywords: | Testosterone, Heavy metals, Immersion, Water, Secretion. |
| Cite Article: | "Immersion of lower limbs in water; Effects of selected heavy metals on testosterone secretion in adult male subjects.", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 8, page no.809 - 817, August-2022, Available :http://www.ijsdr.org/papers/IJSDR2208119.pdf |
| Downloads: | 000337072 |
| Publication Details: | Published Paper ID: IJSDR2208119 Registration ID:201349 Published In: Volume 7 Issue 8, August-2022 DOI (Digital Object Identifier): Page No: 809 - 817 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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