INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Use of GeneXpert (CBNAAT) in diagnosis of SARS-CoV-2
Authors Name:
Dr. Renuka Aniruddha Murhar
, Dr. Sunita Gajbhiye , Dr. Ashwini Patil , Dr. Sunanda Shrikhande
Unique Id:
IJSDR2208105
Published In:
Volume 7 Issue 8, August-2022
Abstract:
ABSTRACT BACKGROUND & OBJECTIVE: The current SARS-CoV-2/COVID-19 pandemic poses significant diagnostic challenges on each level of pre- to post-analytical steps. CBNAAT/ GENEXPERT detects the pan-sarbecovirus E gene and also N2 region of the N gene as its SARS-CoV-2-specific target which helps in the diagnosis of COVID-19 infection. Rapid and simple assays for SARS-CoV-2 detection aid in early diagnosis in emergency situations thus provide important diagnostic information, improve patient management and provide infection control counter measurements. With this background, we estimated the usefulness of CBNAAT in diagnosis of COVID-19 infection. METHODOLOGY: According to the advisory issued by ICMR, nasopharyngeal swabs of 1390 cases were tested by GeneXpert (CBNAAT). RESULTS: Out of the 1390 cases tested, 469 cases (33.6%) were tested positive with a male to female ratio of 3:1. Out of 1390 cases, 1209 (83%) were dead patients and 181(9.2%) were ANC females. CONCLUSION: GeneXpert Xpress SARS-CoV-2 (CBNAAT) is a closed cartridge-based system requires BSL-2 facility with minimal sample handling. GeneXpert is rapid and simple assay for SARS-CoV-2 detection with turn-around time: 50 mins. It is a valuable addition for affording laboratories in situations where rapid and accurate diagnosis are of essence.
"Use of GeneXpert (CBNAAT) in diagnosis of SARS-CoV-2", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 8, page no.713 - 716, August-2022, Available :http://www.ijsdr.org/papers/IJSDR2208105.pdf
Downloads:
000337074
Publication Details:
Published Paper ID: IJSDR2208105
Registration ID:201325
Published In: Volume 7 Issue 8, August-2022
DOI (Digital Object Identifier):
Page No: 713 - 716
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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