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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD OF AZILSARTAN MEDOXOMIL |
| Authors Name: | Manisha |
| Unique Id: | IJSDR2207080 |
| Published In: | Volume 7 Issue 7, July-2022 |
| Abstract: | Azilsartan is used for the treatment hypertension and has reliable results in blood pressure reduction and tolerability. It lowers blood pressure by blocking the action of angiotensin II at the AT1 receptor, a hormone that contracts blood vessels and reduces water excretion through the kidneys. There have been numerous methods developed so far for quantitative estimation of azilsartan in bulk and pharmaceutical dosage form. Pharmaceutical analytical methods include UV Visible Spectrophotometry. Azilsartan Medoxomil is rapidly hydrolysed to the active moiety azilsartan by esterases in the gastrointestinal tract and during drug absorption. In this study, a simple, sensitive and highly accurate ultraviolet spectrophotometry method has been developed and validated for determination of Azilsartan medoxomil. Results of analysis were validated for accuracy, precision, LOD, LOQ etc. parameters were found to be satisfactory. The proposed method in simple, rapid and suitable for the routine analysis. |
| Keywords: | Azilsartan medoxomil, Mechanism, Methanol, Spectrophotometry and Validation |
| Cite Article: | "DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC METHOD OF AZILSARTAN MEDOXOMIL", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.7, Issue 7, page no.558 - 563, July-2022, Available :http://www.ijsdr.org/papers/IJSDR2207080.pdf |
| Downloads: | 000337077 |
| Publication Details: | Published Paper ID: IJSDR2207080 Registration ID:201021 Published In: Volume 7 Issue 7, July-2022 DOI (Digital Object Identifier): Page No: 558 - 563 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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