INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
CLINICOBIOCHEMICAL CORRELATION AND CYTOLOGICAL STUDY OF PLEURAL FLUID
Authors Name:
DR. NAVDEEP KAUR
, DR. REETA DHAR , DR. PUJA S IYENGAR , DR. ARPITA SINGH
Unique Id:
IJSDR2112038
Published In:
Volume 6 Issue 12, December-2021
Abstract:
Effusion means abnormal accumulation of fluid within the body cavities. Cytological examination of fluids is of great diagnostic value in both non-neoplastic and neoplastic effusions. Apart from reporting malignancies, cytological evaluation also reveals information about various inflammatory conditions of serous membranes, fungal, bacterial, parasitic and viral infections. Methods: A prospective study carried out at a tertiary care hospital in Navi Mumbai over a period of 2yrs. A total number of 100 cases were studied. They were examined for physical appearance and color, protein and ADA levels. The pleural fluid was examined for cytomorphological features by using routine and special stains. Results: Out of the 100 cases, 4 cases were clinically diagnosed to be malignant, out of which 2 cases were positive for malignancy on cytological examination. Taking total protein cut off value of 3gm/dl, 65 fluids were exudative and 35 were transudative in nature. 88.2% of the cases diagnosed as tuberculosis with pleural effusion showed raised levels of ADA.A cut off value of 40 U/L of ADA for pleural fluids showed a sensitivity of 88.2%, specificity of 70.1% and a PPV and NPV of 46.8% and 95.2% respectively. Conclusion: Though the cytological examination of the fluids seems to be simple, yet its diagnostic importance is of great significance particularly in cases of malignancy, tuberculosis and peritonitis.
Keywords:
Body fluid, Cytology, Malignancy
Cite Article:
"CLINICOBIOCHEMICAL CORRELATION AND CYTOLOGICAL STUDY OF PLEURAL FLUID", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.6, Issue 12, page no.236 - 242, December-2021, Available :http://www.ijsdr.org/papers/IJSDR2112038.pdf
Downloads:
000336256
Publication Details:
Published Paper ID: IJSDR2112038
Registration ID:193788
Published In: Volume 6 Issue 12, December-2021
DOI (Digital Object Identifier):
Page No: 236 - 242
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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