INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Intracellular and extracellular oxidative stress initiated by reactive oxygen species (ROS) play a major role in skin aging, which is characterized by wrinkles and atypical pigmentation. Although the free radical theory is widely accepted among scientist, certain conflicts regarding the aging process are confronted by clinicians. The free radical theory of aging hypothesizes that damage at the cellular and tissue levels is caused due to oxygen-derived free radicals which are responsible for the age-related changes. In a normal situation, a balanced-equilibrium exists among oxidants, antioxidants and biomolecules. Excess generation of free radicals leads to oxidation and further contributing to cellular functional impairment, and these radicals may overwhelm natural cellular antioxidant defences. The identification of free radical reactions as promoters of the aging process implies that interventions aimed at limiting or inhibiting them should be able to reduce the rate of formation of aging changes with a consequent reduction of the aging rate and disease pathogenesis. The free radicals present bring about a change in the ageing process as they inhibit the formation of free radicals which brings about a consequent change in the aging rate. This paper reviews data regarding the effects of antioxidants on the anti-aging process and longevity. The role of low molecular weight antioxidants and their role in aging and the effects on cardiovascular diseases and cancer was also discussed.
Keywords:
Antioxidant, Free radical, Anti-aging
Cite Article:
"Role of Antioxidants In Antiaging", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.6, Issue 4, page no.676 - 680, April-2021, Available :http://www.ijsdr.org/papers/IJSDR2104111.pdf
Downloads:
000336256
Publication Details:
Published Paper ID: IJSDR2104111
Registration ID:193242
Published In: Volume 6 Issue 4, April-2021
DOI (Digital Object Identifier):
Page No: 676 - 680
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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