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INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
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| Paper Title: | Role Of Remdesivir In Covid-19: A Review Of Pharmacology, Preclinical And Clinical Studies Of Drug. |
| Authors Name: | Dr. Shital Dhawane , Miss. Snehal Dherange , Mr. Shivam Banarase |
| Unique Id: | IJSDR2008013 |
| Published In: | Volume 5 Issue 8, August-2020 |
| Abstract: | In December 2019 the outbreak of corona virus, occurred in Wuhan City, China. COVID-19, which has affected at least 114 countries and more than 608K people dead. On 11 march 2020 the WHO officially declares it a pandemic. As the world scrambles to find a way to prevent corona virus infections, medical experts are evaluating and working on every available lead. Health workers are currently making efforts to control further disease outbreaks caused by the novel CoV-19.Remdesivir shows the therapeutic approach in numerous clinical trials. Remdesivir is a nucleotide analogue prodrug that rattled the viral replication, originally evaluated in clinical trials to oblique the Ebola outbreak in 2014. There are almost ten clinical trials of remdesivir are investigated against COVID-19. The dose for remdesivir is administered through IV rout which is 200 mg on day 1 followed by daily IV maintenance doses of 100 mg for 5–9 days. In this study we overviewed the discovery of remdesivir, mechanism of action, the current clinical trials and the effectiveness of remdesivir. |
| Keywords: | Corona virus, Remdesivir, (GS-5734), SARS-CoV2. |
| Cite Article: | "Role Of Remdesivir In Covid-19: A Review Of Pharmacology, Preclinical And Clinical Studies Of Drug.", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.5, Issue 8, page no.87 - 102, August-2020, Available :http://www.ijsdr.org/papers/IJSDR2008013.pdf |
| Downloads: | 000337071 |
| Publication Details: | Published Paper ID: IJSDR2008013 Registration ID:192264 Published In: Volume 5 Issue 8, August-2020 DOI (Digital Object Identifier): Page No: 87 - 102 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
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