INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15
Microwave Synthesis of 3-methoxy phenyl Triazolothiadiazole Derivatives
Authors Name:
Ms. Bhagyashri D. Jadhav
, Dr. Tushar N. Lokhande
Unique Id:
IJSDR2008010
Published In:
Volume 5 Issue 8, August-2020
Abstract:
6-(substituted phenyl)-3-methoxy phenyl triazolothiadiazole are nucleus for obtaining more biologically active heterocycles. Cyclization with substituted acids gives five six membered heterocycle derivatives. In this research article we noted the synthesis of a series of 1,2 4-triazolo-1,3,4-thiadiazoles starting from 3-methoxy benzohydrazide obtaining 3-methoxy potassium salts which is stir at RT for 16 hrs to form 3-methoxy 1,2,4-triazole which is irradiated in microwave for 3-5 min. with substituted acids using as cyclizing agent like phosphorous oxychloride (PoCl3).
Keywords:
Triazolothiadiazole, 3-Methoxy Benzohydrazide, IR, NMR, GCMS
Cite Article:
"Microwave Synthesis of 3-methoxy phenyl Triazolothiadiazole Derivatives", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.5, Issue 8, page no.67 - 70, August-2020, Available :http://www.ijsdr.org/papers/IJSDR2008010.pdf
Downloads:
000337070
Publication Details:
Published Paper ID: IJSDR2008010
Registration ID:192258
Published In: Volume 5 Issue 8, August-2020
DOI (Digital Object Identifier):
Page No: 67 - 70
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631
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