|
INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH International Peer Reviewed & Refereed Journals, Open Access Journal ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016 open access , Peer-reviewed, and Refereed Journals, Impact factor 8.15 |
Imp Links for Author
Imp Links for Reviewer
Research Area
Subscribe IJSDR
Visitor Counter
Copyright Infringement Claims
Indexing Partner
|
Published Paper Details
|
|
| Paper Title: | METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF CLINDAMYCIN AND MICONAZOLE BY RP-HPLC METHOD |
| Authors Name: | SANA NAVYA , GOPU MANGA DEVI |
| Unique Id: | IJSDR2007131 |
| Published In: | Volume 5 Issue 7, July-2020 |
| Abstract: | A simple, Accurate, precise method was developed for the simultaneous estimation of the Clindamycin and Miconazole in Tablet dosage form. Chromatogram was run through BDS C8 150 x 4.6 mm, 5m. Mobile phase containing Buffer 0.01NKh2PO4 (4.8PH): Acetonitrile taken in the ratio 60:40 was pumped through column at a flow rate of 0.8 ml/min. Buffer used in this method was 0.01NKh2po4 (4.8PH) buffer. Temperature was maintained at 30°C. Optimized wavelength selected was 220.0 nm. Retention time of Clindamycin and Miconazole were found to 2.143 min and 2.949 min %RSD of the Clindamycin and Miconazole were and found to be 0.5 and 0.5 respectively. %Recovery was obtained as 100.67% and 100.28% for Clindamycin and Miconazole respectively. LOD, LOQ values obtained from regression equations of Clindamycin and Miconazole were 0.34, 1.03 and 0.22, 0.66 respectively. Regression equation of Clindamycin is y = 5605.x+5008 y = 9193x+3755 of Miconazole. Retention times were decreased and run time was decreased, so the method developed was simple and economical that can be adopted in regular Quality control test in Industries. |
| Keywords: | Clindamycin, Miconazole, RP-HPLC |
| Cite Article: | "METHOD DEVELOPMENT AND VALIDATION FOR SIMULTANEOUS ESTIMATION OF CLINDAMYCIN AND MICONAZOLE BY RP-HPLC METHOD", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.5, Issue 7, page no.869 - 924, July-2020, Available :http://www.ijsdr.org/papers/IJSDR2007131.pdf |
| Downloads: | 000337070 |
| Publication Details: | Published Paper ID: IJSDR2007131 Registration ID:192199 Published In: Volume 5 Issue 7, July-2020 DOI (Digital Object Identifier): Page No: 869 - 924 Publisher: IJSDR | www.ijsdr.org ISSN Number: 2455-2631 |
|
Click Here to Download This Article |
|
| Article Preview | |
|
|
|
Major Indexing from www.ijsdr.org
| Google Scholar | ResearcherID Thomson Reuters | Mendeley : reference manager | Academia.edu |
| arXiv.org : cornell university library | Research Gate | CiteSeerX | DOAJ : Directory of Open Access Journals |
| DRJI | Index Copernicus International | Scribd | DocStoc |
Track Paper
Important Links
Conference Proposal
ISSN
 |
 |
DOI (A digital object identifier)
  Providing A digital object identifier by DOI How to GET DOI and Hard Copy Related |
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
|
 |
 |
 |
Social Media
Indexing Partner |
|||
| Copyright © 2024 - All Rights Reserved - IJSDR | |||
Facebook Twitter Instagram LinkedIn