Welcome to IJSDR UGC CARE norms ugc approved journal norms IJRTI Research Journal | ISSN : 2455-2631
IJSDR
INTERNATIONAL JOURNAL OF SCIENTIFIC DEVELOPMENT AND RESEARCH
International Peer Reviewed & Refereed Journals, Open Access Journal
ISSN Approved Journal No: 2455-2631 | Impact factor: 8.15 | ESTD Year: 2016
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 8.15 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)

Issue: January 2023

Volume 8 | Issue 1

Impact factor: 8.15

Click Here For more Info

Imp Links for Author
Imp Links for Reviewer
Research Area
Subscribe IJSDR
Visitor Counter

Copyright Infringement Claims
Indexing Partner
Published Paper Details
Paper Title: DEVELOPMENT, OPTIMIZATION AND EVALUATION OF COLLOIDAL NANO-CARRIER SYSTEM
Authors Name: Piyush Pankaj Vishwakarma , K. Saravanan
Unique Id: IJSDR2006057
Published In: Volume 5 Issue 6, June-2020
Abstract: The purpose of this study is to develop and characterize a successful colloidal nano-carrier viz. microemulsion for oral delivery as well as for topical delivery of antigout drug. Gout is a metabolic disorder which causes inflammation of the joints hence the pain. It is the most common crystal arthropathy and induced by the deposition of monosodium urate (MSU) crystal in joint and soft tissues that can produce an acute or chronic arthritis or inflammatory arthritis. The present study will conduct to investigate the microemulsion based drug delivery system of antigout drug febuxostat( FBT) in order to bypass its gastrointestinal adverse effect and to improve patient compliance and hence improve therapeutic efficacy.. Microemulsion will develop and optimize using box behnken design i.e. by using design expert software. The develop microemulsion based gels will characterized for pH, spreadability , drug content, viscosity and transdermal permeability of drug. Optimized gel formulation will then subject to in vitro antigout study in comparison to marketed available formulation of Febuxostat by using monosodium urate (MSU) crystals induced animal model.
Keywords: Febuxostat, microemulsion, microemulsion based gel, antigout, transdermal permeability and topical delivery
Cite Article: "DEVELOPMENT, OPTIMIZATION AND EVALUATION OF COLLOIDAL NANO-CARRIER SYSTEM", International Journal of Science & Engineering Development Research (www.ijsdr.org), ISSN:2455-2631, Vol.5, Issue 6, page no.344 - 357, June-2020, Available :http://www.ijsdr.org/papers/IJSDR2006057.pdf
Downloads: 000201506
Publication Details: Published Paper ID: IJSDR2006057
Registration ID:191974
Published In: Volume 5 Issue 6, June-2020
DOI (Digital Object Identifier):
Page No: 344 - 357
Publisher: IJSDR | www.ijsdr.org
ISSN Number: 2455-2631

Click Here to Download This Article

Article Preview

Click here for Article Preview







Major Indexing from www.ijsdr.org
Google Scholar ResearcherID Thomson Reuters Mendeley : reference manager Academia.edu
arXiv.org : cornell university library Research Gate CiteSeerX DOAJ : Directory of Open Access Journals
DRJI Index Copernicus International Scribd DocStoc

Track Paper
Important Links
Conference Proposal
ISSN
DOI (A digital object identifier)


Providing A digital object identifier by DOI
How to GET DOI and Hard Copy Related
Open Access License Policy
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License
Creative Commons License
This material is Open Knowledge
This material is Open Data
This material is Open Content
Social Media
IJSDR

Indexing Partner